Kundačina, I., Schobesberger, S., Kittler, S., Thumfart, H., Spadiut, O., Ertl, P., Knezevic, N., & Radonic, V. (2025). A Versatile Gold Leaf Immunosensor with a Novel surface functionalization strategy based on protein L and trastuzumab for HER2 detection. Scientific Reports, 15, Article 34. https://doi.org/10.1038/s41598-024-83961-9 ( reposiTUm)

Waldschitz, D., Bartlechner, J., Karner, E. M., Spadiut, O., Jakubek, S., & Kager, J. (2025). Addressing raw material variation: Maintaining a steady-state during cultivation by blending of lignocellulosic feed streams. Biochemical Engineering Journal, 224, Article 109891. https://doi.org/10.1016/j.bej.2025.109891 ( reposiTUm)

Besleaga, M., Zimmermann, C., Ebner, K., Mach, R., Mach-Aigner, A., Geier, M., Glieder, A., Spadiut, O., & Kopp, J. (2024). Bi-directionalized promoter systems allow methanol-free production of hard-to-express peroxygenases with Komagataella Phaffii. Microbial Cell Factories, 23, Article 177. https://doi.org/10.1186/s12934-024-02451-9 ( reposiTUm)

Pittenauer, E., Quehenberger, J., Sedlmayr, V. L., Marchetti-Deschmann, M., & Spadiut, O. (2024). High-energy CID tandem TOF-MS of various types of precursor ions of selected diether phospholipids: Diagnostic known and unexpected fragmentation pathways. International Journal of Mass Spectrometry, 499, 1–12. https://doi.org/10.1016/j.ijms.2024.117237 ( reposiTUm)

Kriechbaum, R., Kronlachner, L., Limbeck, A., Kopp, J., & Spadiut, O. (2024). Towards a circular economy - Repurposing side streams from the potato processing industry by Chlorella vulgaris. Journal of Environmental Management, 366, 1–12. https://doi.org/10.1016/j.jenvman.2024.121796 ( reposiTUm)

Kriechbaum, R., Spadiut, O., & Kopp, J. (2024). Bioconversion of Furanic Compounds by Chlorella vulgaris—Unveiling Biotechnological Potentials. Microorganisms, 12(6), 1–15. https://doi.org/10.3390/microorganisms12061222 ( reposiTUm)

Von Werz, V. M. F., Spadiut, O., & Kozma, B. (2024). A review and statistical analysis to identify and describe relationships between CQAs and CPPs of natural killer cell expansion processes. Cytotherapy, 26(11), 1285–1298. https://doi.org/10.1016/j.jcyt.2024.05.025 ( reposiTUm)

Bus, Y., Waldschitz, D., & Spadiut, O. (2024). mid-IR dataset from low molecular weight permeate of ultra-filtered spent sulfite liquor. Data in Brief, 55, Article 110752. https://doi.org/10.1016/j.dib.2024.110752 ( reposiTUm)

Grivalský, T., Lakatos, G. E., Štěrbová, K., Manoel, J. A. C., Beloša, R., Divoká, P., Kopp, J., Kriechbaum, R., Spadiut, O., Zwirzitz, A., Trenzinger, K., & Masojídek, J. (2024). Poly-β-hydroxybutyrate production by Synechocystis MT_a24 in a raceway pond using urban wastewater. Applied Microbiology and Biotechnology, 108(1), 1–12. https://doi.org/10.1007/s00253-023-12924-3 ( reposiTUm)

Sedlmayr, V. L., Schobesberger, S., Spitz, S., Ertl, P., Wurm, D. J., Quehenberger, J., & Spadiut, O. (2024). Archaeal ether lipids improve internalization and transfection with mRNA lipid nanoparticles. European Journal of Pharmaceutics and Biopharmaceutics, 197, Article 114213. https://doi.org/10.1016/j.ejpb.2024.114213 ( reposiTUm)

Kastenhofer, J., Spadiut, O., Papangelakis, V., & Allen, D. G. (2024). Roles of pH and phosphate in rare earth element biosorption with living acidophilic microalgae. Applied Microbiology and Biotechnology, 108(1), Article 262. https://doi.org/10.1007/s00253-024-13068-8 ( reposiTUm)

Waldschitz, D., Bus, Y., Herwig, C., Kager, J., & Spadiut, O. (2024). Addressing raw material variability: In-line FTIR sugar composition analysis of lignocellulosic process streams. Bioresource Technology, 399, Article 130535. https://doi.org/10.1016/j.biortech.2024.130535 ( reposiTUm)

Schlögel, G., Lück, R., Kittler, S., Spadiut, O., Kopp, J., Zanghellini, J., & Gotsmy, M. (2024). Optimizing bioprocessing efficiency with OptFed: Dynamic nonlinear modeling improves product-to-biomass yield. Computational and Structural Biotechnology Journal, 23, 3651–3661. https://doi.org/10.34726/7759 ( reposiTUm)

Vidakovic, I., Karin, K., Fiedler, D., Khinast, J., Fröhlich, E., Leitinger, G., Horn, C., Quehenberger, J., Spadiut, O., & Prassl, R. (2024). Archaeosomes for Oral Drug Delivery: From Continuous Microfluidics Production to Powdered Formulations. Pharmaceutics, 16(6), Article 694. https://doi.org/10.3390/pharmaceutics16060694 ( reposiTUm)

Igwe, C. L., Müller, D. F., Gisperg, F., Pauk, J. N., Kierein, M., Elshazly, M., Klausser, R., Kopp, J., Spadiut, O., & Přáda Brichtová, E. (2024). Online monitoring of protein refolding in inclusion body processing using intrinsic fluorescence. Analytical and Bioanalytical Chemistry, 416(12), 3019–3032. https://doi.org/10.1007/s00216-024-05249-1 ( reposiTUm)

Igwe, C. L., Gisperg, F., Kierein, M., Brichtová, E. P., Spadiut, O., & Müller, D. F. (2024). Mechanistic soft-sensor design for protein refolding processes based on intrinsic fluorescence measurements. COMPUTERS & CHEMICAL ENGINEERING, 187, 1–11. https://doi.org/10.1016/j.compchemeng.2024.108734 ( reposiTUm)

Sedlmayr, V. L., Luger, M., Pittenauer, E., Marchetti-Deschmann, M., Kronlachner, L., Limbeck, A., Raunjak, P., Quehenberger, J., & Spadiut, O. (2024). Development of a defined medium for the heterotrophic cultivation of Metallosphaera sedula. Extremophiles, 28(3), Article 36. https://doi.org/10.1007/s00792-024-01348-0 ( reposiTUm)

Waldschitz, D., Neudert, M.-R., Kitzmüller, J., Lachmann, J., Fonteyne, A., Maes, K., Bar, N., Sinner, P., & Spadiut, O. (2024). Robust, fully quantifiable and scalable bioprocess utilizing spent sulfite liquor with Corynebacterium glutamicum. Bioresource Technology, 406, Article 130967. https://doi.org/10.1016/j.biortech.2024.130967 ( reposiTUm)

Igwe, C. L., Pauk, J. N., Müller, D. F., Jaeger, M., Deuschitz, D., Hartmann, T., & Spadiut, O. (2024). Comprehensive evaluation of recombinant lactate dehydrogenase production from inclusion bodies. Journal of Biotechnology, 379, 65–77. https://doi.org/10.1016/j.jbiotec.2023.11.006 ( reposiTUm)

Waldschitz, D., Neudert, M.-R., Kitzmüller, J., Bong, J. H., Bus, Y., Karner, E. M., Sinner, P., & Spadiut, O. (2024). Antimicrobial peptide production with Corynebacterium glutamicum on lignocellulosic side streams. BIOTECHNOLOGY FOR BIOFUELS AND BIOPRODUCTS, 17(1), Article 147. https://doi.org/10.1186/s13068-024-02587-1 ( reposiTUm)

Szabadi, A., Klausser, R., Spadiut, O., & Schröder, C. (2024). Inclusion Bodies in Ionic Liquids. Liquids, 4(1), 1–31. https://doi.org/10.3390/liquids4010001 ( reposiTUm)

Wisniewski, A., Humer, D. C., Möller, M., Kanje, S., Spadiut, O., & Hober, S. (2024). Targeted HER2-positive cancer therapy using ADAPT6 fused to horseradish peroxidase. New Biotechnology, 83, 74–81. https://doi.org/10.1016/j.nbt.2024.07.001 ( reposiTUm)

Sedlmayr, V. L., Széliová, D., De Kock, V., Gansemans, Y., Van Nieuwerburgh, F., Peeters, E., Quehenberger, J., Zanghellini, J., & Spadiut, O. (2024). Impact of nutrient excess on physiology and metabolism of Sulfolobus acidocaldarius. Frontiers in Microbiology, 15, Article 1475385. https://doi.org/10.3389/fmicb.2024.1475385 ( reposiTUm)

Besleaga, M., Vignolle, G. A., Kopp, J., Spadiut, O., Mach, R. L., Mach-Aigner, A. R., & Zimmermann, C. (2023). Evaluation of reference genes for transcript analyses in Komagataella phaffii (Pichia pastoris). Fungal Biology and Biotechnology, 10, Article 7. https://doi.org/10.1186/s40694-023-00154-1 ( reposiTUm)

Klausser, R., Kopp, J., Prada, E., Gisperg, F., Elshazly, M., & Spadiut, O. (2023). State-of-the-art and novel approaches to mild solubilization of inclusion bodies. Frontiers in Bioengineering and Biotechnology, 11, 1249196. https://doi.org/10.3389/fbioe.2023.1249196 ( reposiTUm)

Sedlmayr, V., Horn, C., Wurm, D. J., Spadiut, O., & Quehenberger, J. (2023). Archaeosomes facilitate storage and oral delivery of cannabidiol. International Journal of Pharmaceutics, 645, Article 123434. https://doi.org/10.1016/j.ijpharm.2023.123434 ( reposiTUm)

Rastädter, K., Wurm, D. J., Spadiut, O., & Quehenberger, J. (2023). kLa based scale-up cultivation of the extremophilic archaeon Sulfolobus acidocaldarius: from benchtop to pilot scale. Frontiers in Bioengineering and Biotechnology, 11, 1160012. https://doi.org/10.3389/fbioe.2023.1160012 ( reposiTUm)

Kriechbaum, R., Serna Loaiza, S., Friedl, A., Spadiut, O., & Kopp, J. (2023). Utilizing straw-derived hemicellulosic hydrolysates by Chlorella vulgaris: Contributing to a biorefinery approach. Journal of Applied Phycology. https://doi.org/10.1007/s10811-023-03082-0 ( reposiTUm)

Ramaswamy, K., Johnson, R. L., Winter, S. D., Worthy, H. L., Thomas, C., Humer, D. C., Spadiut, O., Hindson, S. H., Wells, S., Barratt, A. H., Menzies, G., Pudney, C. R., & Jones, D. D. (2023). Glycosylation increases active site rigidity leading to improved enzyme stability and turnover. FEBS Journal, 290(15), 3812–3827. https://doi.org/10.1111/febs.16783 ( reposiTUm)

Doppler, P., Kriechbaum, R., & Spadiut, O. (2022). High-throughput characterization of the filamentous cyanobacterium Anabaena sp. using flow cytometry. Journal of Microbiological Methods, 199, Article 106510. https://doi.org/10.1016/j.mimet.2022.106510 ( reposiTUm)

Knezevic, K., Rastädter, K., Quehenberger, J., Spadiut, O., Krampe, J., & Kreuzinger, N. (2022). Circular production – Evaluation of membrane technologies for nutrient recycling from a microbial fermentation effluent. Journal of Cleaner Production, 377, 1–13. https://doi.org/10.1016/j.jclepro.2022.134436 ( reposiTUm)

Akhgar, C. K., Ebner, J., Spadiut, O., Schwaighofer, A., & Lendl, B. (2022). QCL-IR Spectroscopy for In-Line Monitoring of Proteins from Preparative Ion-Exchange Chromatography. Analytical Chemistry. https://doi.org/10.1021/acs.analchem.1c05191 ( reposiTUm)

Hausjell, J., Weissensteiner, J., Molitor, C., Schlangen, K., Spadiut, O., & Halbwirth, H. (2022). First purified recombinant CYP75B including transmembrane helix with unexpected high substrate specificity to (2R)-naringenin. Scientific Reports, 12(1), Article 8548. https://doi.org/10.1038/s41598-022-11556-3 ( reposiTUm)

Kopp, J., Bayer, B., Slouka, C., Striedner, G., Dürkop, M., & Spadiut, O. (2022). Fundamental insights in early-stage inclusion body formation. Microbial Biotechnology, 00. https://doi.org/10.1111/1751-7915.14117 ( reposiTUm)

Akhgar, C. K., Ebner, J., Alcaraz, M., Kopp, J., Goicoechea, H., Spadiut, O., Schwaighofer, A., & Lendl, B. (2022). Application of Quantum Cascade Laser-Infrared Spectroscopy and Chemometrics for In-Line Discrimination of Coeluting Proteins from Preparative Size Exclusion Chromatography. Analytical Chemistry, 94(32), 11192–11200. https://doi.org/10.1021/acs.analchem.2c01542 ( reposiTUm)

Kittler, S., Ebner, J., Besleaga, M., Larsbrink, J., Darnhofer, B., Birner-Grünberger, R., Schobesberger, S., Akhgar, C. K., Schwaighofer, A., Lendl, B., & Spadiut, O. (2022). Recombinant Protein L: Production, Purification and Characterization of a Universal Binding Ligand. Journal of Biotechnology, 359, 108–115. https://doi.org/10.1016/j.jbiotec.2022.10.002 ( reposiTUm)

Rastädter, K., Tramontano, A., Wurm, D. J., Spadiut, O., & Quehenberger, J. (2022). Flow cytometry-based viability staining: an at-line tool for bioprocess monitoring of Sulfolobus acidocaldarius. AMB Express, 12, Article 107. https://doi.org/10.1186/s13568-022-01447-1 ( reposiTUm)

Gundinger, T., Kittler, S., Kubicek, S., Kopp, J., & Spadiut, O. (2022). Recombinant Protein Production in E. coli Using the phoA Expression System. Fermentation, 8(4), Article 181. https://doi.org/10.3390/fermentation8040181 ( reposiTUm)

Doppler, P., Kriechbaum, R., Käfer, M., Kopp, J., Remias, D., & Spadiut, O. (2022). Coelastrella terrestris for Adonixanthin Production: Physiological Characterization and Evaluation of Secondary Carotenoid Productivity. Marine Drugs, 20(3), Article 175. https://doi.org/10.3390/md20030175 ( reposiTUm)

Škulj, S., Barišić, A., Mutter, N., Spadiut, O., Barišić, I., & Bertosa, B. (2022). Effect of N-glycosylation on horseradish peroxidase structural and dynamical properties. Computational and Structural Biotechnology Journal, 20, 3096–3105. https://doi.org/10.1016/j.csbj.2022.06.008 ( reposiTUm)

Kastenhofer, J., Libiseller-Egger, J., Rajamanickam, V., & Spadiut, O. (2021). Monitoring E. coli Cell Integrity by ATR-FTIR Spectroscopy and Chemometrics: Opportunities and Caveats. Processes, 9(3), 422. https://doi.org/10.3390/pr9030422 ( reposiTUm)

Kastenhofer, J., Rajamanickam, V., Libiseller-Egger, J., & Spadiut, O. (2021). Monitoring and control of E. coli cell integrity. Journal of Biotechnology, 329, 1–12. https://doi.org/10.1016/j.jbiotec.2021.01.009 ( reposiTUm)

Kastenhofer, J., Cataldo, A. L., Ebner, J., Sedlmayr, V. L., Jungbauer, A., & Spadiut, O. (2021). Economic and ecological benefits of a leaky E. coli strain for downstream processing: a case study for staphylococcal protein A. Journal of Chemical Technology and Biotechnology, 96(6), 1667–1674. https://doi.org/10.1002/jctb.6691 ( reposiTUm)

Schottroff, F., Kastenhofer, J., Spadiut, O., Jaeger, H., & Wurm, D. J. (2021). Selective Release of Recombinant Periplasmic Protein From E. coli Using Continuous Pulsed Electric Field Treatment. Frontiers in Bioengineering and Biotechnology, 8. https://doi.org/10.3389/fbioe.2020.586833 ( reposiTUm)

Pekarsky, A., Michor, H., & Spadiut, O. (2021). Revisiting the Potential Functionality of the MagR Protein. Magnetochemistry, 7(11), 147. https://doi.org/10.3390/magnetochemistry7110147 ( reposiTUm)

Kastenhofer, J., Libiseller-Egger, J., Rajamanickam, V., & Spadiut, O. (2021). Monitoring E. coli Cell Integrity by ATR-FTIR Spectroscopy and Chemometrics: Opportunities and Caveats. Processes, 9(3), 1–17. https://doi.org/10.3390/pr9030422 ( reposiTUm)

Kittler, S., Besleaga, M., Ebner, J., & Spadiut, O. (2021). Protein L—More Than Just an Affinity Ligand. Processes, 9(5), 1–13. https://doi.org/10.3390/pr9050874 ( reposiTUm)

Kittler, S., Slouka, C., Pell, A., Lamplot, R., Besleaga, M., Ablasser, S., Herwig, C., Spadiut, O., & Kopp, J. (2021). Cascaded processing enables continuous upstream processing with E. coli BL21(DE3). Scientific Reports, 11, 1–11. https://doi.org/10.1038/s41598-021-90899-9 ( reposiTUm)

Ebner, J., Humer, D., Klausser, R., Rubus, V., Pell, R., Spadiut, O., & Kopp, J. (2021). At-Line Reversed Phase Liquid Chromatography for In-Process Monitoring of Inclusion Body Solubilization. Bioengineering, 8(6), 1–13. https://doi.org/10.3390/bioengineering8060078 ( reposiTUm)

Pekarsky, A., Reininger, M., & Spadiut, O. (2021). The impact of technical failures on recombinant production of soluble proteins in Escherichia coli: a case study on process and protein robustness. Bioprocess and Biosystems Engineering, 44(6), 1049–1061. https://doi.org/10.1007/s00449-021-02514-w ( reposiTUm)

Humer, D., Furlanetto, V., Schruef, A.-K., Wlodarczyk, A., Kuttke, M., Divne, C., & Spadiut, O. (2021). Potential of unglycosylated horseradish peroxidase variants for enzyme prodrug cancer therapy. Biomedicine and Pharmacotherapy, 142(112037), 112037. https://doi.org/10.1016/j.biopha.2021.112037 ( reposiTUm)

Humer, D., & Spadiut, O. (2021). Enzyme prodrug therapy: cytotoxic potential of paracetamol turnover with recombinant horseradish peroxidase. Monatshefte Für Chemie - Chemical Monthly, 152(11), 1389–1397. https://doi.org/10.1007/s00706-021-02848-x ( reposiTUm)

Ebner, J., Humer, D., Klausser, R., Rubus, V., Pell, R., Spadiut, O., & Kopp, J. (2021). At-Line Reversed Phase Liquid Chromatography for In-Process Monitoring of Inclusion Body Solubilization. Bioengineering, 8(6), 78. https://doi.org/10.3390/bioengineering8060078 ( reposiTUm)

Kittler, S., Besleaga, M., Ebner, J., & Spadiut, O. (2021). Protein L-More Than Just an Affinity Ligand. Processes, 9(5), 874. https://doi.org/10.3390/pr9050874 ( reposiTUm)

Weissensteiner, J., Molitor, C., Marinovic, S., Führer, L., Waqas Hassan, S., Hutabarat, O. S., Spornberger, A., Stich, K., Hausjell, J., Spadiut, O., Haselmair-Gosch, C., & Halbwirth, H. (2021). Molecular and Enzymatic Characterization of Flavonoid 3′-Hydroxylase of Malus × domestica. Plants, 10(9), 1956. https://doi.org/10.3390/plants10091956 ( reposiTUm)

Pekarsky, A., Reininger, M., & Spadiut, O. (2021). The impact of technical failures on recombinant production of soluble proteins in Escherichia coli: a case study on process and protein robustness. Bioprocess and Biosystems Engineering, 44(6), 1049–1061. https://doi.org/10.1007/s00449-021-02514-w ( reposiTUm)

Mittermair, S., Richter, J., Doppler, P., Trenzinger, K., Nicoletti, C., Forsich, C., Spadiut, O., Herwig, C., & Lackner, M. (2021). Impact of exoD gene knockout on the polyhydroxybutyrate overaccumulating mutant Mt_a24. International Journal of Biobased Plastics, 3(1), 1–18. https://doi.org/10.1080/24759651.2020.1863020 ( reposiTUm)

Doppler, P., Kornpointner, C., Halbwirth, H., Remias, D., & Spadiut, O. (2021). Tetraedron minimum, First Reported Member of Hydrodictyaceae to Accumulate Secondary Carotenoids. Life, 11(2), 107. https://doi.org/10.3390/life11020107 ( reposiTUm)

Rastädter, K., Wurm, D. J., Spadiut, O., & Quehenberger, J. (2021). Physiological Characterization of Sulfolobus acidocaldarius in a Controlled Bioreactor Environment. International Journal of Environmental Research and Public Health, 18(11), 5532. https://doi.org/10.3390/ijerph18115532 ( reposiTUm)

Doppler, P., Kriechbaum, R., Singer, B., & Spadiut, O. (2021). Make microalgal cultures axenic again - a fast and simple workflow utilizing fluorescence-activated cell sorting. Journal of Microbiological Methods, 186(106256), 106256. https://doi.org/10.1016/j.mimet.2021.106256 ( reposiTUm)

Jodlbauer, J., Rohr, T., Spadiut, O., Mihovilovic, M. D., & Rudroff, F. (2021). Biocatalysis in Green and Blue: Cyanobacteria. Trends in Biotechnology, 39(9), 875–889. https://doi.org/10.1016/j.tibtech.2020.12.009 ( reposiTUm)

Doppler, P., Gasser, C., Kriechbaum, R., Ferizi, A., & Spadiut, O. (2021). In Situ Quantification of Polyhydroxybutyrate in Photobioreactor Cultivations of Synechocystis sp. Using an Ultrasound-Enhanced ATR-FTIR Spectroscopy Probe. Bioengineering, 8(9), 1–10. https://doi.org/10.3390/bioengineering8090129 ( reposiTUm)

Schwaighofer, A., Ablasser, S., Lux, L., Kopp, J., Herwig, C., Spadiut, O., Lendl, B., & Slouka, C. (2020). Production of Active Recombinant Hyaluronidase Inclusion Bodies from Apis mellifera in E. coli Bl21(DE3) and characterization by FT-IR Spectroscopy. International Journal of Molecular Sciences, 54(44), 1–14. https://doi.org/10.3390/ijms21113881 ( reposiTUm)

Kopp, J., Kittler, S., Slouka, C., Herwig, C., Spadiut, O., & Wurm, D. J. (2020). Repetitive Fed-Batch: A Promising Process Mode for Biomanufacturing With E. coli. Frontiers in Bioengineering and Biotechnology, 8. https://doi.org/10.3389/fbioe.2020.573607 ( reposiTUm)

Kastenhofer, J., Rettenbacher, L., Feuchtenhofer, L., Mairhofer, J., & Spadiut, O. (2020). Inhibition of E. coli Host RNA Polymerase Allows Efficient Extracellular Recombinant Protein Production by Enhancing Outer Membrane Leakiness. Biotechnology Journal, 16(3), 2000274. https://doi.org/10.1002/biot.202000274 ( reposiTUm)

Kastenhofer, J., & Spadiut, O. (2020). Culture medium density as a simple monitoring tool for cell integrity of Escherichia coli. Journal of Biotechnology, 324, Article 100017. https://doi.org/10.1016/j.btecx.2020.100017 ( reposiTUm)

Pekarsky, A., Mihalyi, S., Weiss, M., Limbeck, A., & Spadiut, O. (2020). Depletion of Boric Acid and Cobalt from Cultivation Media: Impact on Recombinant Protein Production with Komagataella pha i. Bioengineering, 7(4), 161. https://doi.org/10.3390/bioengineering7040161 ( reposiTUm)

Pekarsky, A., & Spadiut, O. (2020). Intrinsically Magnetic Cells: A Review on Their Natural Occurrence and Synthetic Generation. Frontiers in Bioengineering and Biotechnology, 8, Article 573183. https://doi.org/10.3389/fbioe.2020.573183 ( reposiTUm)

Rastädter, K., Wurm, D. J., Spadiut, O., & Quehenberger, J. (2020). The Cell Membrane of Sulfolobus spp.-Homeoviscous Adaption and Biotechnological Applications. International Journal of Molecular Sciences, 21(11), 1–22. https://doi.org/10.3390/ijms21113935 ( reposiTUm)

Hausjell, J., Schendl, D., Weissensteiner, J., Molitor, C., Halbwirth, H., & Spadiut, O. (2020). Recombinant production of a hard-to-express membranebound cytochrome P450 in different yeasts-Comparison of physiology and productivity. Yeast, 37(2), 217–226. https://doi.org/10.1002/yea.3441 ( reposiTUm)

Gundinger, T., & Spadiut, O. (2020). pH conditioning is a crucial step in primary recovery - A case study for a recombinant Fab from E. coli. Protein Expression and Purification, 165(105504), 105504. https://doi.org/10.1016/j.pep.2019.105504 ( reposiTUm)

Quehenberger, J., Steudler, S., & Spadiut, O. (2020). Evaluation of the potential of an enzymatically treated beech wood hydrolysate as carbon source for Sulfolobus acidocaldarius. Bioresource Technology Reports, 9(100362), 100362. https://doi.org/10.1016/j.biteb.2019.100362 ( reposiTUm)

Quehenberger, J., Pittenauer, E., Allmaier, G., & Spadiut, O. (2020). The influence of the specific growth rate on the lipid composition of Sulfolobus acidocaldarius. Extremophiles, 24(3), 413–420. https://doi.org/10.1007/s00792-020-01165-1 ( reposiTUm)

Doppler, P., Veiter, L., Spadiut, O., Herwig, C., & Rajamanickam, V. (2020). A Chemometric Tool to Monitor and Predict Cell Viability in Filamentous Fungi Bioprocesses Using UV Chromatogram Fingerprints. Processes, 8(4), 461. https://doi.org/10.3390/pr8040461 ( reposiTUm)

Eggenreich, B., Wurm, D. J., Rajamanickam, V., Klausser, R., Slouka, C., & Spadiut, O. (2020). High pressure homogenization is a key unit operation in inclusion body processing. Journal of Biotechnology, 324(100022), 100022. https://doi.org/10.1016/j.btecx.2020.100022 ( reposiTUm)

Brunauer, G. C., Spadiut, O., Gruber, A., & Slouka, C. (2020). Yeast Propagation Control: Low Frequency Electrochemical Impedance Spectroscopy as an Alternative for Cell Counting Chambers in Brewery Applications. Chemosensors, 8(2), 27. https://doi.org/10.3390/chemosensors8020027 ( reposiTUm)

Spadiut, O., Gundinger, T., Pittermann, B., & Slouka, C. (2020). Spatially Resolved Effects of Protein Freeze-Thawing in a Small-Scale Model Using Monoclonal Antibodies. Pharmaceutics, 12(4), 382. https://doi.org/10.3390/pharmaceutics12040382 ( reposiTUm)

Kopp, J., Zauner, F. B., Pell, A., Hausjell, J., Humer, D., Ebner, J., Herwig, C., Spadiut, O., Slouka, C., & Pell, R. (2020). Development of a generic reversed-phase liquid chromatography method for protein quantification using analytical quality-by-design principles. Journal of Pharmaceutical and Biomedical Analysis, 188(113412), 113412. https://doi.org/10.1016/j.jpba.2020.113412 ( reposiTUm)

Gandini, R., Reichenbach, T., Spadiut, O., Tan, T.-C., Kalyani, D. C., & Divne, C. (2020). A Transmembrane Crenarchaeal Mannosyltransferase Is Involved in N-Glycan Biosynthesis and Displays an Unexpected Minimal Cellulose-Synthase-like Fold. Journal of Molecular Biology, 432(16), 4658–4672. https://doi.org/10.1016/j.jmb.2020.06.016 ( reposiTUm)

Hausjell, J., Kutscha, R., Gesson, J. D., Reinisch, D., & Spadiut, O. (2020). The Effects of Lactose Induction on a Plasmid-Free E. coli T7 Expression System. Bioengineering, 7(1), 8. https://doi.org/10.3390/bioengineering7010008 ( reposiTUm)

Horvat, J., Narat, M., & Spadiut, O. (2020). The effect of amino acid supplementation in an industrial Chinese Hamster Ovary process. Biotechnology Progress, 36(5). https://doi.org/10.1002/btpr.3001 ( reposiTUm)

Humer, D., Ebner, J., & Spadiut, O. (2020). Scalable High-Performance Production of Recombinant Horseradish Peroxidase from E. coli Inclusion Bodies. International Journal of Molecular Sciences, 21(13), 4625. https://doi.org/10.3390/ijms21134625 ( reposiTUm)

Rajamanickam, V., Herwig, C., & Spadiut, O. (2019). A Generic Workflow for Bioprocess Analytical Data: Screening Alignment Techniques and Analyzing their Effects on Multivariate Modeling. Biochemistry & Analytical Biochemistry, 8(1), 11. http://hdl.handle.net/20.500.12708/142949 ( reposiTUm)

Humer, D., & Spadiut, O. (2019). Improving the Performance of Horseradish Peroxidase by Site-Directed Mutagenesis. International Journal of Molecular Sciences, 20(4), 916. https://doi.org/10.3390/ijms20040916 ( reposiTUm)

Slouka, C., Kopp, J., Strohmer, D., Kager, J., Spadiut, O., & Herwig, C. (2019). Monitoring and control strategies for inclusion body production in E. coli based on glycerol consumption. Journal of Biotechnology, 296, 75–82. https://doi.org/10.1016/j.jbiotec.2019.03.014 ( reposiTUm)

Quehenberger, J., Albersmeier, A., Glatzel, H., Hackl, M., Kalinowski, J., & Spadiut, O. (2019). A defined cultivation medium for Sulfolobus acidocaldarius. Journal of Biotechnology, 301, 56–67. https://doi.org/10.1016/j.jbiotec.2019.04.028 ( reposiTUm)

Pekarsky, A., Spadiut, O., Rajamanickam, V., & Wurm, D. J. (2019). A fast and simple approach to optimize the unit operation high pressure homogenization - a case study for a soluble therapeutic protein in E. coli. Preparative Biochemistry & Biotechnology, 49(1), 74–81. https://doi.org/10.1080/10826068.2018.1536988 ( reposiTUm)

Kopp, J., Slouka, C., Spadiut, O., & Herwig, C. (2019). The Rocky Road From Fed-Batch to Continuous Processing With E. coli. Frontiers in Bioengineering and Biotechnology, 7. https://doi.org/10.3389/fbioe.2019.00328 ( reposiTUm)

Kopp, J., Kolkmann, A.-M., Veleenturf, P. G., Spadiut, O., Herwig, C., & Slouka, C. (2019). Boosting Recombinant Inclusion Body Production-From Classical Fed-Batch Approach to Continuous Cultivation. Frontiers in Bioengineering and Biotechnology, 7. https://doi.org/10.3389/fbioe.2019.00297 ( reposiTUm)

Slouka, C., Kopp, J., Spadiut, O., & Herwig, C. (2019). Perspectives of inclusion bodies for bio-based products: curse or blessing? Applied Microbiology and Biotechnology. https://doi.org/10.1007/s00253-018-9569-1 ( reposiTUm)

Beisl, S., Quehenberger, J., Kamravamanesh, D., Spadiut, O., & Friedl, A. (2019). Exploitation of Wheat Straw Biorefinery Side Streams as Sustainable Substrates for Microorganisms: A Feasibility Study. Processes, 7(12), 956. https://doi.org/10.3390/pr7120956 ( reposiTUm)

Pekarsky, A., Konopek, V., & Spadiut, O. (2019). The impact of technical failures during cultivation of an inclusion body process. Bioprocess and Biosystems Engineering, 42, 1611–1624. https://doi.org/10.1007/s00449-019-02158-x ( reposiTUm)

Quehenberger, J., Reichenbach, T., Baumann, N., Rettenbacher, L., Divne, C., & Spadiut, O. (2019). Kinetics and Predicted Structure of a Novel Xylose Reductase from Chaetomium thermophilum. International Journal of Molecular Sciences, 20(1), 1–17. https://doi.org/10.3390/ijms20010185 ( reposiTUm)

Hausjell, J., Miltner, M., Herzig, C., Limbeck, A., Saracevic, Z., Saračević, E., Weissensteiner, J., Molitor, C., Halbwirth, H., & Spadiut, O. (2019). Valorisation of cheese whey as substrate and inducer for recombinant protein production in E. coli HMS174(DE3). Bioresource Technology Reports, 8, Article 100340. https://doi.org/10.1016/j.biteb.2019.100340 ( reposiTUm)

Wurm, D. J., Quehenberger, J., Mildner, J., Eggenreich, B., Slouka, C., Schwaighofer, A., Wieland, K., Lendl, B., Rajamanickam, V., Herwig, C., & Spadiut, O. (2018). Teaching an old pET new tricks: tuning of inclusion body formation and properties by a mixed feed system in E. coli. Applied Microbiology and Biotechnology, 102(2), 667–676. https://doi.org/10.1007/s00253-017-8641-6 ( reposiTUm)

Pekarsky, A., Veiter, L., Rajamanickam, V., Herwig, C., Grünwald-Gruber, C., Altmann, F., & Spadiut, O. (2018). Production of a recombinant peroxidase in different glyco‑engineered Pichia pastoris strains: a morphological and physiological comparison. Microbial Cell Factories, 17(183). https://doi.org/10.1186/s12934-018-1032-6 ( reposiTUm)

Wasinger, C., Hofer, A., Spadiut, O., & Hohenegger, M. (2018). Amino Acid Signature in Human Melanoma Cell Lines from Different Disease Stages. Scientific Reports, 8(6245). https://doi.org/10.1038/s41598-018-24709-0 ( reposiTUm)

Kopp, J., Slouka, C., Ulonska, S., Kager, J., Fricke, J., Spadiut, O., & Herwig, C. (2018). Impact of Glycerol as Carbon Source onto Specific Sugar and Inducer Uptake Rates and Inclusion Body Productivity in E. coli BL21(DE3). Bioengineering, 5(1), 1. https://doi.org/10.3390/bioengineering5010001 ( reposiTUm)

Humer, D., & Spadiut, O. (2018). Wanted: more monitoring and control during inclusion body processing. World Journal of Microbiology and Biotechnology, 34(158). https://doi.org/10.1007/s11274-018-2541-5 ( reposiTUm)

Eggenreich, B., Scholz, E., Wurm, D. J., Forster, F., & Spadiut, O. (2018). The production of a recombinant tandem single chain fragment variable capable of binding prolamins triggering celiac disease. BMC Biotechnology, 18(30). https://doi.org/10.1186/s12896-018-0443-0 ( reposiTUm)

Quehenberger, J., & Spadiut, O. (2018). Symbiose von biologischen und chemischen Katalysatoren zur Umsetzung von Hemicellulose. GIT Labor-Fachzeitschrift, 62(2), 34–36. http://hdl.handle.net/20.500.12708/145315 ( reposiTUm)

Kurbanoglu, S., Zafar, M. N., Tasca, F., Aslam, I., Spadiut, O., Leech, D., Haltrich, D., & Gorton, L. (2018). Amperometric Flow Injection Analysis of Glucose and Galactose Based on Engineered Pyranose 2-Oxidases and Osmium Polymers for Biosensor Applications. Electroanalysis, 30(7), 1496–1504. https://doi.org/10.1002/elan.201800096 ( reposiTUm)

Gundinger, T., Pansy, A., & Spadiut, O. (2018). A sensitive and robust HPLC method to quantify recombinant antibody fragments in E. coli crude cell lysate. Journal of Chromatography B, 1083, 242–248. https://doi.org/10.1016/j.jchromb.2018.02.044 ( reposiTUm)

Hausjell, J., Halbwirth, H., & Spadiut, O. (2018). Recombinant production of eukaryotic cytochrome P450s in microbial cell factories. Bioscience Reports, 38(2). https://doi.org/10.1042/bsr20171290 ( reposiTUm)

Hofer, A., Herwig, C., & Spadiut, O. (2018). Lecithin is the key material attribute in soy bean oil affecting filamentous bioprocesses. AMB Express, 8, 1–8. https://doi.org/10.1186/s13568-018-0625-0 ( reposiTUm)

Kopp, J., Slouka, C., Strohmer, D., Kager, J., Spadiut, O., & Herwig, C. (2018). Inclusion Body Bead Size in E. coli Controlled by Physiological Feeding. Microorganisms, 6(4), 116. https://doi.org/10.3390/microorganisms6040116 ( reposiTUm)

Hausjell, J., Weissensteiner, J., Molitor, C., Halbwirth, H., & Spadiut, O. (2018). E. coli HMS174(DE3) is a sustainable alternative to BL21(DE3). Microbial Cell Factories, 17(169). https://doi.org/10.1186/s12934-018-1016-6 ( reposiTUm)

Spadiut, O. (2018). Inclusion bodies - more than just waste! Biochemistry and Molecular Biology Journal, 04. https://doi.org/10.21767/2471-8084-c2-011 ( reposiTUm)

Rajamanickam, V., Herwig, C., & Spadiut, O. (2018). Data Science, Modeling, and Advanced PAT Tools Enable Continuous Culture. BioProcess International, 16(4), 20–25. http://hdl.handle.net/20.500.12708/144446 ( reposiTUm)

Maleiner, B., Tomasch, J., Heher, P., Spadiut, O., Rünzler, D., & Fuchs, C. (2018). The Importance of Biophysical and Biochemical Stimuli in Dynamic Skeletal Muscle Models. Frontiers in Physiology, 9. https://doi.org/10.3389/fphys.2018.01130 ( reposiTUm)

Rajamanickam, V., Wurm, D., Slouka, C., Herwig, C., & Spadiut, O. (2017). A novel toolbox for E. coli lysis monitoring. Analytical and Bioanalytical Chemistry, 409(3), 667–671. https://doi.org/10.1007/s00216-016-9907-z ( reposiTUm)

Kubizek, F., Eggenreich, B., & Spadiut, O. (2017). Status Quo in Antibody-Drug Conjugates - Can Glyco-Enzymes Solve the Current Challenges? Protein and Peptide Letters, 24(8). https://doi.org/10.2174/0929866524666170724105211 ( reposiTUm)

Danneels, B., Tanghe, M., Joosten, H.-J., Gundinger, T., Spadiut, O., Stals, I., & Desmet, T. (2017). A quantitative indicator diagram for lytic polysaccharide monooxygenases reveals the role of aromatic surface residues in HjLPMO9A regioselectivity. PLoS ONE, 12(5), e0178446. https://doi.org/10.1371/journal.pone.0178446 ( reposiTUm)

Gundinger, T., & Spadiut, O. (2017). A comparative approach to recombinantly produce the plant enzymehorseradish peroxidase in Escherichia coli. Journal of Biotechnology, 248, 15–24. https://doi.org/10.1016/j.jbiotec.2017.03.003 ( reposiTUm)

Wurm, D. J., Hausjell, J., Ulonska, S., Herwig, C., & Spadiut, O. (2017). Mechanistic platform knowledge of concomitant sugar uptake in Escherichia coli BL21(DE3) strains. Scientific Reports, 7(45072). https://doi.org/10.1038/srep45072 ( reposiTUm)

Wurm, D. J., Slouka, C., Bosilj, T., Herwig, C., & Spadiut, O. (2017). How to trigger periplasmic release in recombinant Escherichia coli: A comparative analysis. Engineering in Life Sciences, 17(2), 215–222. http://hdl.handle.net/20.500.12708/146474 ( reposiTUm)

Spadiut, O. (2017). How to tune recombinant protein production in E. coli for enhanced production of biopharmaceuticals? Journal of Biotechnology & Biomaterials, 07(01). https://doi.org/10.4172/2155-952x.c1.070 ( reposiTUm)

Wurm, D. J., Marschall, L., Sagmeister, P., Herwig, C., & Spadiut, O. (2017). Simple monitoring of cell leakiness and viability in Escherichia coli bioprocesses-A case study. Engineering in Life Sciences, 17(6), 598–604. http://hdl.handle.net/20.500.12708/146647 ( reposiTUm)

Rajamanickam, V., Krippl, M., Herwig, C., & Spadiut, O. (2017). An automated data-driven DSP development approach for glycoproteins from yeast. ELECTROPHORESIS, 38, 2886–2891. http://hdl.handle.net/20.500.12708/147626 ( reposiTUm)

Quehenberger, J., Shen, L., Albers, S.-V., Siebers, B., & Spadiut, O. (2017). Sulfolobus - A Potential Key Organism in Future Biotechnology. Frontiers in Microbiology, 8. https://doi.org/10.3389/fmicb.2017.02474 ( reposiTUm)

Rajamanickam, V., Metzger, K., Schmid, C., & Spadiut, O. (2017). A novel bi-directional promoter system allows tunable recombinant protein production in Pichia pastoris. Microbial Cell Factories, 16, 1–7. https://doi.org/10.1186/s12934-017-0768-8 ( reposiTUm)

Eggenreich, B., Rajamanickam, V., Wurm, D. J., Fricke, J., Herwig, C., & Spadiut, O. (2017). A combination of HPLC and automated data analysis for monitoring the efficiency of high-pressure homogenization. Microbial Cell Factories, 16, 1–10. https://doi.org/10.1186/s12934-017-0749-y ( reposiTUm)

Slouka, C., Wurm, D., Brunauer, G., Welzl-Wachter, A., Spadiut, O., Fleig, J., & Herwig, C. (2016). A Novel Application for Low Frequency Electrochemical Impedance Spectroscopy as an Online Process Monitoring Tool for Viable Cell Concentrations. Sensors, 16(11), 1900. https://doi.org/10.3390/s16111900 ( reposiTUm)

Eggenreich, B., Willim, M., Wurm, D. J., Herwig, C., & Spadiut, O. (2016). Production strategies for active heme-containing peroxidases from E. coli inclusion bodies - a review. Biotechnology Reports, 10, 75–83. https://doi.org/10.1016/j.btre.2016.03.005 ( reposiTUm)

Bonifert, G., Folkes, L., Gmeiner, C., Dachs, G., & Spadiut, O. (2016). Recombinant horseradish peroxidase variants for targeted cancer treatment. Cancer Medicine, 5(6), 1194–1203. http://hdl.handle.net/20.500.12708/149212 ( reposiTUm)

Rajamanickam, V., Winkler, M., Flotz, P., Meyer, L., Herwig, C., & Spadiut, O. (2016). Comparison of Purification Strategies of Three Horseradish Peroxidase Isoenzymes Recombinantly Produced in Pichia pastoris. Journal of Chromatography & Separation Techniques, 07(01). https://doi.org/10.4172/2157-7064.1000316 ( reposiTUm)

Spadiut, O., Wurm, D. J., Veiter, L., Ulonska, S., Eggenreich, B., & Herwig, C. (2016). The E. coli pET expression system revisited—mechanistic correlation between glucose and lactose uptake. Applied Microbiology and Biotechnology, 100, 8721–8729. https://doi.org/10.1007/s00253-016-7620-7 ( reposiTUm)

Spadiut, O., & Herwig, C. (2015). Mikroben zur Herstellung monoklonaler Antikörper und Antikörperfragmente. BIOspektrum, 21(3), 281–283. http://hdl.handle.net/20.500.12708/150829 ( reposiTUm)

Krainer, F. W., Capone, S., Jäger, M., Vogl, T., Gerstmann, M., Glieder, A., Herwig, C., & Spadiut, O. (2015). Optimizing cofactor availability for the production of recombinant heme peroxidase in Pichia pastoris. Microbial Cell Factories, 14(4). https://doi.org/10.1186/s12934-014-0187-z ( reposiTUm)

Reinsch, H., Spadiut, O., Heidingsfelder, J., & Herwig, C. (2015). Examining the freezing process of an intermediate bulk containing an industrially relevant protein. Enzyme and Microbial Technology, 71, 13–19. https://doi.org/10.1016/j.enzmictec.2015.01.003 ( reposiTUm)

Rajamanickam, V., Herwig, C., & Spadiut, O. (2015). Monoliths in Bioprocess Technology. Chromatography, 2(2), 195–212. https://doi.org/10.3390/chromatography2020195 ( reposiTUm)

Gmeiner, C., & Spadiut, O. (2015). Effects of different media supplements on the production of an active recombinant plant peroxidase in a Pichia pastoris Δoch1 strain. Bioengineered, 6(3), 175–178. https://doi.org/10.1080/21655979.2015.1036208 ( reposiTUm)

Gmeiner, C., Saadati, A., Maresch, D., Krasteva, S., Frank, M., Altmann, F., Herwig, C., & Spadiut, O. (2015). Development of a fed-batch process for a recombinant Pichia pastoris Δoch1 strain expressing a plant peroxidase. Microbial Cell Factories, 14(1). https://doi.org/10.1186/s12934-014-0183-3 ( reposiTUm)

Capone, S., Ćorajević, L., Bonifert, G., Murth, P., Maresch, D., Altmann, F., Herwig, C., & Spadiut, O. (2015). Combining Protein and Strain Engineering for the Production of Glyco-Engineered Horseradish Peroxidase C1A in Pichia pastoris. International Journal of Molecular Sciences, 16(10), 23127–23142. https://doi.org/10.3390/ijms161023127 ( reposiTUm)

Capone, S., Horvat, J., Herwig, C., & Spadiut, O. (2015). Development of a mixed feed strategy for a recombinant Pichia pastoris strain producing with a de-repression promoter. Microbial Cell Factories, 14(101). https://doi.org/10.1186/s12934-015-0292-7 ( reposiTUm)

Capone, S., Pletzenauer, R., Maresch, D., Metzger, K., Altmann, F., Herwig, C., & Spadiut, O. (2014). Glyco-variant library of the versatile enzyme horseradish peroxidase. Glycobiology, 24(9), 852–863. https://doi.org/10.1093/glycob/cwu047 ( reposiTUm)

Larsbrink, J., Rogers, T. E., Hemsworth, G. R., McKee, L. S., Tauzin, A. S., Spadiut, O., Klinter, S., Pudlo, N. A., Urs, K., Koropatkin, N. M., Creagh, A. L., Haynes, C. A., Kelly, A. G., Cederholm, S. N., Davies, G. J., Martens, E. C., & Brumer, H. (2014). A discrete genetic locus confers xyloglucan metabolism in select human gut Bacteroidetes. Nature, 506(7489), 498–502. https://doi.org/10.1038/nature12907 ( reposiTUm)

Spadiut, O., Capone, S., Krainer, F., Glieder, A., & Herwig, C. (2014). Microbials for the production of monoclonal antibodies and antibody fragments. Trends in Biotechnology, 32(1), 54–60. https://doi.org/10.1016/j.tibtech.2013.10.002 ( reposiTUm)

Ullmann, E., Tan, T. C., Gundinger, T., Herwig, C., Divne, C., & Spadiut, O. (2014). A novel cytosolic NADH:quinone oxidoreductase from Methanothermobacter marburgensis. Bioscience Reports, 34(6). https://doi.org/10.1042/bsr20140143 ( reposiTUm)

Krainer, F., Pletzenauer, R., Rossetti, L., Herwig, C., Glieder, A., & Spadiut, O. (2014). Purification and basic biochemical characterization of 19 recombinant plant peroxidase isoenzymes produced in Pichia pastoris. Protein Expression and Purification, 95, 104–112. https://doi.org/10.1016/j.pep.2013.12.003 ( reposiTUm)

Tan, T. C., Spadiut, O., Gandini, R., Haltrich, D., & Divne, C. (2014). Structural Basis for Binding of Fluorinated Glucose and Galactose to Trametes multicolor Pyranose 2-Oxidase Variants with Improved Galactose Conversion. PLoS ONE, 9(1), e86736. https://doi.org/10.1371/journal.pone.0086736 ( reposiTUm)

Anasontzis, G. E., Salazar, M. P., Spadiut, O., Brumer, H., & Olsson, L. (2014). Effects of Temperature and Glycerol and Methanol-Feeding Profiles on the Production of Recombinant Galactose Oxidase in Pichia pastoris. Biotechnology Progress, 30(3), 728–735. http://hdl.handle.net/20.500.12708/157241 ( reposiTUm)

Spadiut, O., & Herwig, C. (2014). Dynamics in bioprocess development for Pichia pastoris. BIOENGINEERED, 5(6), 401–404. https://doi.org/10.4161/bioe.36152 ( reposiTUm)

Spadiut, O., Zalai, D., Dietzsch, C., & Herwig, C. (2014). Quantitative comparison of dynamic physiological feeding profiles for recombinant protein production with Pichia pastoris. Bioprocess and Biosystems Engineering, 37(6), 1163–1172. https://doi.org/10.1007/s00449-013-1087-z ( reposiTUm)

Sagmeister, P., Schimek, C., Meitz, A., Herwig, C., & Spadiut, O. (2014). Tunable recombinant protein expression with E. coli in a mixed-feed environment. Applied Microbiology and Biotechnology, 98, 2937–2945. http://hdl.handle.net/20.500.12708/156535 ( reposiTUm)

Krainer, F. W., Gmeiner, C., Neutsch, L., Windwarder, M., Pletzenauer, R., Herwig, C., Altmann, F., Glieder, A., & Spadiut, O. (2013). Knockout of an endogenous mannosyltransferase increases the homogeneity of glycoproteins produced in Pichia pastoris. Scientific Reports, 3(3279). https://doi.org/10.1038/srep03279 ( reposiTUm)

Frischmann, A., Neudl, S., Gaderer, R., Bonazza, K., Zach, S., Gruber, S. G., Spadiut, O., Friedbacher, G., Grothe, H., & Seidl-Seiboth, V. (2013). Self-assembly at Air/Water Interfaces and Carbohydrate Binding Properties of the Small Secreted Protein EPL1 from the fungus Trichoderma atroviride. Journal of Biological Chemistry, 288(6), 4278–4287. https://doi.org/10.1074/jbc.m112.427633 ( reposiTUm)

Spadiut, O., & Herwig, C. (2013). Production and purification of the multifunctional enzyme horseradish peroxidase. Pharmaceutical Bioprocessing, 1(3), 283–295. http://hdl.handle.net/20.500.12708/154555 ( reposiTUm)

Posch, A. E., Herwig, C., & Spadiut, O. (2013). Science-based bioprocess design for filamentous fungi. Trends in Biotechnology, 31(1), 37–44. https://doi.org/10.1016/j.tibtech.2012.10.008 ( reposiTUm)

Dietzsch, C., Spadiut, O., & Herwig, C. (2013). On-line multiple component analysis for efficient quantitative bioprocess development. Journal of Biotechnology, 163(4), 362–370. https://doi.org/10.1016/j.jbiotec.2012.03.010 ( reposiTUm)

Spadiut, O., Rittmann, S., Dietzsch, C., & Herwig, C. (2013). Dynamic process conditions in bioprocess development. ENGINEERING IN LIFE SCIENCES, 13, 88–101. http://hdl.handle.net/20.500.12708/154865 ( reposiTUm)

Zalai, D., Dietzsch, C., Herwig, C., & Spadiut, O. (2012). A Dynamic Fed Batch Strategy for a Pichia Pastoris Mixed feed System to Increase Process Understanding. Biotechnology Progress, 28(3), 878–886. http://hdl.handle.net/20.500.12708/163779 ( reposiTUm)

Krainer, F. W., Dietzsch, C., Hajek, T., Herwig, C., Spadiut, O., & Glieder, A. (2012). Recombinant protein expression in Pichia pastoris strains with an engineered methanol utilization pathway. Microbial Cell Factories, 11(22). https://doi.org/10.1186/1475-2859-11-22 ( reposiTUm)

Posch, A. E., Spadiut, O., & Herwig, C. (2012). Switching industrial production processes from complex to defined media : method development and case study using the example of Penicillium chrysogenum. Microbial Cell Factories, 11(88). https://doi.org/10.1186/1475-2859-11-88 ( reposiTUm)

Posch, A. E., Spadiut, O., & Herwig, C. (2012). A novel method for fast and statistically verified morphological characterization of filamentous fungi. Fungal Genetics and Biology, 49(7), 499–510. https://doi.org/10.1016/j.fgb.2012.05.003 ( reposiTUm)

Spadiut, O., Rossetti, L., Dietzsch, C., & Herwig, C. (2012). Purification of a recombinant plant peroxidase produced in Pichia pastoris by a simple 2-step strategy. Protein Expression and Purification, 86(2), 89–97. https://doi.org/10.1016/j.pep.2012.09.008 ( reposiTUm)

Spadiut, O., Dietzsch, C., Posch, A., & Herwig, C. (2012). Evaluating online sampling probes for substrate concentration and protein production by a Design of Experiments screening approach. ENGINEERING IN LIFE SCIENCES, 12(5), 507–513. http://hdl.handle.net/20.500.12708/164052 ( reposiTUm)

Dietzsch, C., Spadiut, O., & Herwig, C. (2011). A dynamic method based on the specific substrate uptake rate to set up a feeding strategy for Pichia pastoris. Microbial Cell Factories, 10(14). https://doi.org/10.1186/1475-2859-10-14 ( reposiTUm)

Dietzsch, C., Spadiut, O., & Herwig, C. (2011). A fast approach to determine a fed batch feeding profile for recombinant Pichia pastoris strains. Microbial Cell Factories, 10(85). https://doi.org/10.1186/1475-2859-10-85 ( reposiTUm)

Pisanelli, I., Kujawa, M., Gschnitzer, D., Spadiut, O., Seiboth, B., & Peterbauer, C. (2010). Heterologous expression of an Agaricus meleagris pyranose dehydrogenase-encoding gene in Aspergillus spp. and characterization of the recombinant enzyme. Applied Microbiology and Biotechnology, 86(2), 599–606. https://doi.org/10.1007/s00253-009-2308-x ( reposiTUm)

Akhgar, C. K., Ebner, J., Spadiut, O., Schwaighofer, A., & Lendl, B. (2022). Laser-based mid-infrared spectroscopy enables in-line detection of protein secondary structure from preparative liquid chromatography. In Z. Huang (Ed.), Biomedical Vibrational Spectroscopy 2022: Advances in Research and Industry. SPIE. https://doi.org/10.34726/2261 ( reposiTUm)

Spadiut, O. (2021). Extracellular Protein Production with E. coli - How Can It Be Done and What Does It Really Bring for the DSP? In Abstracts (p. 1). http://hdl.handle.net/20.500.12708/49663 ( reposiTUm)

Spadiut, O. (2021). Scalable and efficient recombinant production of the versatile plant enzyme horseradish peroxidase. In Abstracts (p. 1). http://hdl.handle.net/20.500.12708/50833 ( reposiTUm)

Spadiut, O. (2019). The Time Has Come - More Control in Inclusion Body Processing. In Abstracts (p. 1). http://hdl.handle.net/20.500.12708/50490 ( reposiTUm)

Doppler, P., & Spadiut, O. (2019). A world without petroleum-based plastics. In 18. Österreichische Chemietage (p. 1). http://hdl.handle.net/20.500.12708/50545 ( reposiTUm)

Spadiut, O. (2019). The Time has come to Bring QbD to Inclusion Body Processing. In Abstracts (p. 1). http://hdl.handle.net/20.500.12708/49951 ( reposiTUm)

Molitor, C., Weissensteiner, J., Hausjell, J., Gandini, R., Divne, C., Spadiut, O., & Halbwirth, H. (2019). Heterologous expression of chalcone 3-hydroxylase from Dahlia variabilis in E.coli as a soluble enzyme. In book of abstracts for posters (p. 1). http://hdl.handle.net/20.500.12708/50646 ( reposiTUm)

Weissensteiner, J., Nitarska, D., Molitor, C., Führer, L., Hausjell, J., Spadiut, O., & Halbwirth, H. (2019). Characterization of a full-size CYP75A in Euphorbia pulcherima. In book of abstracts for posters (p. 1). http://hdl.handle.net/20.500.12708/50644 ( reposiTUm)

Kastenhofer, J., Wurm, D. J., Mairhofer, G., Striedner, G., & Spadiut, O. (2018). A growth decoupled E. coli expression system allows high-yield recombinant production of antibody fragments. In Abstract Book (p. 177). http://hdl.handle.net/20.500.12708/50330 ( reposiTUm)

Wurm, D. J., Eggenreich, B., Herwig, C., Berghammer, G., & Spadiut, O. (2018). The time has come: lntroducing QbD into inclusion body refolding processes. In Abstract Book (p. 88). http://hdl.handle.net/20.500.12708/50327 ( reposiTUm)

Pekarsky, A., Eggenreich, B., Wurm, D. J., & Spadiut, O. (2018). A success story - lnclusion bodies are more than molecular waste. In Abstract Book (p. 178). http://hdl.handle.net/20.500.12708/50329 ( reposiTUm)

Spadiut, O., & Forster, F. (2018). Medizinprodukte aus dem Bioreaktor. In Abstracts. Blickpunkt Forschung: Materialinnovationen @ TU Wien, Wien, Austria. http://hdl.handle.net/20.500.12708/50404 ( reposiTUm)

Kopp, J., Slouka, C., Ulonska, S., Kager, J., Fricke, J., Spadiut, O., & Herwig, C. (2018). Impact of glycerol as carbon source onto specific sugar and inducer uptake rates and inclusion body productivity in E. coli BL21 (DE3). In Abstract Booklet (p. 48). http://hdl.handle.net/20.500.12708/50292 ( reposiTUm)

Kopp, J., Slouka, C., Ulonska, S., Kager, J., Fricke, J., Spadiut, O., & Herwig, C. (2018). Impact of glycerol as carbon source onto specific sugar and inducer uptake rates and inclusion body productivity in E. coli BL21(DE3). In Book of Abstracts (p. 1). http://hdl.handle.net/20.500.12708/50288 ( reposiTUm)

Hausjell, J., Wurm, D. J., Weissensteiner, J., Halbwirth, H., & Spadiut, O. (2018). Using the sustainable waste product Lactose as versatile substance in E. coli bioprocesses. In Book of Abstracts (p. 1). http://hdl.handle.net/20.500.12708/50297 ( reposiTUm)

Spadiut, O. (2018). Antibody Fragments on a Novel Tandem Fab against Celiac Disease - From Inclusion Body to Product Formulation. In Abstracts (p. 18). http://hdl.handle.net/20.500.12708/50240 ( reposiTUm)

Hausjell, J., Weissensteiner, J., Halbwirth, H., & Spadiut, O. (2017). Recombinant production and purification of chalcone-3-hydroxylase (ch3h) from yeast. In Book of Abstracts (pp. 70–71). http://hdl.handle.net/20.500.12708/49872 ( reposiTUm)

Spadiut, O., Rajamanickam, V., Laukens, B., & Callewaert, N. (2017). Glycoengineering of Biopharmaceuticals by Using Glycoengineered Yeasts. In CBM12 Lecture Abstracts (p. 38). http://hdl.handle.net/20.500.12708/49785 ( reposiTUm)

Wurm, D. J., Herwig, C., & Spadiut, O. (2017). Teaching an old pET new Tricks Expression - Tuning in E.coli BL21(DE3). In Book of Abstracts (pp. 50–51). http://hdl.handle.net/20.500.12708/50062 ( reposiTUm)

Gundinger, T., & Spadiut, O. (2017). A comparative approach to recombinantly produce the plant enzyme horseradish peroxidase in Escherichia coli. In Book of Abstracts (pp. 48–49). http://hdl.handle.net/20.500.12708/50854 ( reposiTUm)

Hausjell, J., Weissensteiner, J., Halbwirth, H., & Spadiut, O. (2017). Challenges in the recombinant production of plant proteins in microbial expression hosts. In Abstract and Programme Book (p. 60). http://hdl.handle.net/20.500.12708/49874 ( reposiTUm)

Weissensteiner, J., Hausjell, J., Roth, B. L., Spadiut, O., Stich, K., & Halbwirth, H. (2017). Heterologous expression of cytochrome P450 dependent enzymes. In Abstract and Programme Book (p. 76). http://hdl.handle.net/20.500.12708/49877 ( reposiTUm)

Rajamanickam, V., Herwig, C., & Spadiut, O. (2016). Implementaion of Monolithic Chromatography for Efficient Purification of Recombinant Glycoproteins from Yeast. In Abstract Book (p. 38). http://hdl.handle.net/20.500.12708/49287 ( reposiTUm)

Rajamanickam, V., Wurm, D. J., Herwig, C., & Spadiut, O. (2016). A Novel PAT Toolbox to Facilitate Monitoring of E. Coli Bioprocess. In Abstract Book (p. 16). http://hdl.handle.net/20.500.12708/49286 ( reposiTUm)

Rajamanickam, V., Metzger, K., Glieder, A., & Spadiut, O. (2016). Novel bi-directional promoter systems for tunable recombinant protein expression in Pichia pastoris. In Abstract Book (p. 54). http://hdl.handle.net/20.500.12708/49430 ( reposiTUm)

Gmeiner, C., Saadati, A., Maresch, D., Krasteva, S., Frank, M., Altmann, F., Herwig, C., & Spadiut, O. (2016). Development of a fed-batch process for a recombinant Pichia pastoris Δoch1 strain expressing a plant peroxidase. In Abstract Book (p. 27). http://hdl.handle.net/20.500.12708/49418 ( reposiTUm)

Rajamanickam, V., Capone, S., Herwig, C., & Spadiut, O. (2016). Impurity monitoring of a recombinant SuperMan5 strain during dynamic upstream process. In Abstract Book (p. 30). http://hdl.handle.net/20.500.12708/49426 ( reposiTUm)

Bonifert, G., Folkes, L., Gmeiner, C., Herwig, C., Dachs, G., & Spadiut, O. (2016). Recombinant horseradish peroxidase variants for targeted cancer treatment. In Abstract Book (p. 50). http://hdl.handle.net/20.500.12708/49427 ( reposiTUm)

Capone, S., Horvat, J., Herwig, C., & Spadiut, O. (2016). Development of a mixed feed strategy for a recombinant Pichia pastoris strain producing with a de-repression promoter. In Abstract Book (p. 51). http://hdl.handle.net/20.500.12708/49428 ( reposiTUm)

Rajamanickam, V., Herwig, C., & Spadiut, O. (2016). DSP development for small glycoproteins from yeast using monolithic supports. In Abstract Book (p. 53). http://hdl.handle.net/20.500.12708/49429 ( reposiTUm)

Wurm, D. J., & Spadiut, O. (2015). Two online tools to discriminate between intact, leaky and lysed E. coli cells. In Tagungsband (p. 82). http://hdl.handle.net/20.500.12708/49094 ( reposiTUm)

Gmeiner, C., Maresch, D., Altmann, F., Herwig, C., & Spadiut, O. (2014). Development of a fed-batch process for a Pichia pastoris OCH1 knock-out strain. In Abstract Book (p. 201). http://hdl.handle.net/20.500.12708/48726 ( reposiTUm)

Herwig, C., & Spadiut, O. (2014). Trends for successful biopharmaceutical productions - Future challenges in process and facility design. In Book of Abstracts (p. 13). http://hdl.handle.net/20.500.12708/48561 ( reposiTUm)

Krainer, F., Gmeiner, C., Neutsch, L., Pletzenauer, R., Windwarder, M., Altmann, F., Glieder, A., & Spadiut, O. (2014). Knockout of an endogenous mannosyltransferase increases the homogeneity of glycoproteins produced in Pichia pastoris. In Pichia 2014 (p. 24). http://hdl.handle.net/20.500.12708/48727 ( reposiTUm)

Spadiut, O., & Herwig, C. (2013). Stability studies with the multifunctional enzyme horseradish peroxidase. In Book of Abstracts (p. 25). http://hdl.handle.net/20.500.12708/48230 ( reposiTUm)

Spadiut, O., Dietzsch, C., Krainer, F., Hajek, T., Glieder, A., & Herwig, C. (2012). Playing with the methanol utilization pathway in Pichia pastoris. In Abstract Book (pp. 43–44). http://hdl.handle.net/20.500.12708/47756 ( reposiTUm)

Dietzsch, C., Spadiut, O., Zalai, D., & Herwig, C. (2012). From Strain to Product : A fast approach in bioprocess development for recombinant protein expression in Pichia pastoris. In Abstract Book (pp. 69–70). http://hdl.handle.net/20.500.12708/47757 ( reposiTUm)

Frischmann, A., Zach, S., Gruber, S. G., Spadiut, O., Rodler, A., & Seidl-Seiboth, V. (2012). Self-assembly at air/water interfaces and chitin-binding properties of the small cell wall protein EPL1 from Trichoderma atroviride. In Meeting Abstracts. ECFG 11 - 11#^{th} European Conference on Fungal Genetics, Marburg, Deutschland, EU. http://hdl.handle.net/20.500.12708/47808 ( reposiTUm)

Seidl-Seiboth, V., Zach, S., Frischmann, A., Spadiut, O., Dietzsch, C., Herwig, C., & Kubicek, C. P. (2012). Functional analysis and structural features of fungal LysM chitin-binding proteins. In Abstract Book 2012 (p. 91). http://hdl.handle.net/20.500.12708/47920 ( reposiTUm)

Dietzsch, C., Spadiut, O., Zalai, D., & Herwig, C. (2012). A fast approach in bioprocess development for recombinant protein expression in Pichia pastoris ( Effiziente Bioprozessentwicklung für rekombinante Proteinexpression in Pichia pastoris). In Chemie Ingenieur Technik (p. 1341). http://hdl.handle.net/20.500.12708/47868 ( reposiTUm)

Dietzsch, C., Spadiut, O., Zalai, D., & Herwig, C. (2012). A fast approach in bioprocess development for recombinant protein expression in Pichia pastoris. In Poster Abstracts 2012 (p. 14). http://hdl.handle.net/20.500.12708/47873 ( reposiTUm)

Dietzsch, C., Spadiut, O., Zalai, D., & Herwig, C. (2012). A fast approach in bioprocess development for recombinant protein expression in Pichia pastoris. In Abstract Book 2012 (pp. 94–95). http://hdl.handle.net/20.500.12708/47872 ( reposiTUm)

Dietzsch, C., Spadiut, O., & Herwig, C. (2011). A dynamic method based on the specific substrate uptake rate to set up a feeding strategy for Pichia pastoris. In Abstract Book (p. 72). http://hdl.handle.net/20.500.12708/47262 ( reposiTUm)

Kopp, J., & Spadiut, O. (2023). Inclusion Bodies: Status Quo and Perspectives. In J. Kopp & O. Spadiut (Eds.), Inclusion Bodies : Methods and Protocols (Vol. 2617, pp. 1–13). Humana. https://doi.org/10.1007/978-1-0716-2930-7_1 ( reposiTUm)

Pekarsky, A., & Spadiut, O. (2022). Dynamic Feeding for Pichia pastoris. In V. Mapelli & M. Bettiga (Eds.), Yeast Metabolic Engineering (Vol. 2513, pp. 243–254). https://doi.org/10.1007/978-1-0716-2399-2_14 ( reposiTUm)

Kittler, S., Kopp, J., Patrick Gwen, V., Spadiut, O., Delvigne, F., Herwig, C., & Slouka, C. (2021). The Lazarus Escherichia coli Effect: Recovery of Productivity on Glycerol/Lactose Mixed Feed in Continuous Biomanufacturing. In Frontiers in Bioengineering and Biotechnology. Frontiers. https://doi.org/10.3389/fbioe.2020.00993 ( reposiTUm)

Kopp, J., & Spadiut, O. (2021). A Guideline to Set Up Cascaded Continuous Cultivation with E. coli Bl21 (DE3). In K. Turksen (Ed.), Bioreactors in Stem Cell Biology (Vol. 2436, pp. 223–240). https://doi.org/10.1007/7651_2021_424 ( reposiTUm)

Wurm, D. J., & Spadiut, O. (2019). Purification of Recombinant Glycoproteins from Pichia pastoris Culture Supernatants. In B. Gasser & D. Mattanovich (Eds.), Recombinant Protein Production in Yeast (pp. 343–350). Springer Science + Business Media. https://doi.org/10.1007/978-1-4939-9024-5_17 ( reposiTUm)

Wurm, D. J., & Spadiut, O. (2019). Efficient Development of a Mixed Feed Process for Pichia pastoris. In B. Gasser & D. Mattanovich (Eds.), Recombinant Protein Production in Yeast (pp. 323–333). Springer Science + Business Media. https://doi.org/10.1007/978-1-4939-9024-5_15 ( reposiTUm)

Rajamanickam, V., Sagmeister, P., Spadiut, O., & Herwig, C. (2018). Impurity Monitoring as Novel PAT Tool for Continuous Biopharmaceutical Processes. In Continuous Bioprocessing - Industry Best Practices (pp. 89–101). Repligen. http://hdl.handle.net/20.500.12708/29768 ( reposiTUm)

Wurm, D. J., Herwig, C., & Spadiut, O. (2017). How to Determine lnterdependencies of Glucose and Lactose Uptake Rates for Heterologous Protein Production with E. Coli. In N. A. Burgess-Brown (Ed.), Heterologous Gene Expression in E.coli. Methods in Molecular Biology (pp. 397–408). Humana Press. https://doi.org/10.1007/978-1-4939-6887-9_26 ( reposiTUm)

Gmeiner, C., & Spadiut, O. (2015). Protein Production with a Pichia pastoris OCH1 Knockout Strain in Fed-Batch Mode. In A. Castilho (Ed.), Glyco-Engineering (Vol. 1321, pp. 91–101). Springer Science + Business Media. https://doi.org/10.1007/978-1-4939-2760-9_7 ( reposiTUm)

Spadiut, O., Dietzsch, C., & Herwig, C. (2014). Determination of a Dynamic Feeding Strategy for Recombinant Pichia pastoris Strains. In V. Mapelli (Ed.), Yeast Metabolic Engineering (pp. 185–194). Springer-Verlag. https://doi.org/10.1007/978-1-4939-0563-8_11 ( reposiTUm)

Kopp, J., & Spadiut, O. (Eds.). (2023). Inclusion Bodies : Methods and Protocols (Vol. 2617). Springer. https://doi.org/10.1007/978-1-0716-2930-7 ( reposiTUm)

Spadiut, O. (2024, March 20). Mild Solubilisation of Inclusion Bodies—Quo Vadis? [Conference Presentation]. Bioprocessing Summit Europe 2024, Barcelona, Spain. http://hdl.handle.net/20.500.12708/208949 ( reposiTUm)

Spadiut, O. (2024). Novel PAT and data science tools in inclusion body processing [Conference Presentation]. Biotalk 2024, Germany. http://hdl.handle.net/20.500.12708/208950 ( reposiTUm)

Spadiut, O. (2024). Archeal Ether Lipids Improve Internalization and Transfection with mRNA Lipid Nanoparticles [Conference Presentation]. Liposome Research Days 2024, United Kingdom of Great Britain and Northern Ireland (the). http://hdl.handle.net/20.500.12708/208951 ( reposiTUm)

von Werz, V., Szarzynski, A., Siebold, M., Zigon-Branc, S., Kozma, B., & Spadiut, O. (2024, October 9). Process Development for allogeneic NK cell production [Poster Presentation]. Young Scientist Workshop “Technologies for Cell and Gene Therapies - from Research to Industry", Frankfurt, Germany. http://hdl.handle.net/20.500.12708/208234 ( reposiTUm)

Prada, E., Igwe, C. L., Müller, D. F., Gisperg, F., Pauk, J. N., Kierein, M., Elshazly, M., Klausser, R., Kopp, J., & Spadiut, O. (2024, April 10). Online monitoring of protein refolding in inclusion body processing using intrinsic fluorescence [Conference Presentation]. 8th BioProScale Symposium, Berlin, Germany. http://hdl.handle.net/20.500.12708/208484 ( reposiTUm)

Igwe, C. L., Gisperg, F., Kierein, M., Přáda Brichtová, E., Spadiut, O., & Müller, D. F. (2024, April 9). Mechanistic soft-sensor design for protein refolding processes based on intrinsic fluorescence measurements [Poster Presentation]. 8th BioProScale Symposium 2024, Berlin, Germany. http://hdl.handle.net/20.500.12708/208311 ( reposiTUm)

Spadiut, O. (2023, November). A Peroxidase from Inclusion Bodies as valuable Tool in Breast Cancer Treatment [Conference Presentation]. International Conference on the Separation of Proteins, Peptides and Polynucleotides (ISPPP 2003), Wien, Austria. http://hdl.handle.net/20.500.12708/192327 ( reposiTUm)

Spadiut, O. (2023, July 28). Digitalization in Industry [Conference Presentation]. Salzburg Summit 2023, Austria. ( reposiTUm)

Kriechbaum, R., Kopp, J., & Spadiut, O. (2023, December 12). Repurposing side streams from the potato processing industry by Chlorella vulgaris [Poster Presentation]. AlgaEurope 23, Prag, Czechia. ( reposiTUm)

Spadiut, O. (2023, March 16). Production and Purification of Archaeal Lipids for Enhanced  mRNA Delivery [Conference Presentation]. Bioprocessing Summit Europe 2023, Barcelona, Spain. ( reposiTUm)

Besleaga, M., Ebner, K., Ertl, S., Glieder, A., Spadiut, O., & Kopp, J. (2023, November). Bi-directional promoter systems allow methanol-free production of hard to express unspecific peroxygenases with Komagataella phaffii [Poster Presentation]. PEGS Europe 2023 - Protein & Antibody Engineering Summit, Lisbon, Portugal. http://hdl.handle.net/20.500.12708/192731 ( reposiTUm)

Spadiut, O. (2023, April 11). Monitoring E. coli Cell Integrity by ATR-FTIR Spectroscopy and Chemometrics: Opportunities and Caveats [Presentation]. ANAKON 2023, Wien, Austria. http://hdl.handle.net/20.500.12708/212575 ( reposiTUm)

Kittler, S., Ebner, J., Kopp, J., & Spadiut, O. (2022, March). Small scale mechanical cell disruption: A workflow to screen for ideal disruption conditions for recombinantly produced proteins in E. coli [Poster Presentation]. 7th BioProscale 2022, Berlin, Germany. ( reposiTUm)

Spadiut, O. (2022). A Peroxidase from Inclusion Bodies as Tool in Cancer Treatment [Conference Presentation]. Bioprocessing Summit Europe, Spain. http://hdl.handle.net/20.500.12708/152570 ( reposiTUm)

Kriechbaum, R., Kopp, J., & Spadiut, O. (2022, December 13). Novel tools and strategies for the production of bioplastics in cyanos [Poster Presentation]. Algaeurope 2022, Rom, Italy. ( reposiTUm)

Kriechbaum, R., Kopp, J., & Spadiut, O. (2022, June 9). Potential of Lignocellulic Waste as Substrate for Microalgal Cultivation [Conference Presentation]. Elevating Nordic Algal Biotechnology 2022 (NAS22), Turku, Finland. ( reposiTUm)

Kriechbaum, R., Serna Loaiza, S., Kopp, J., & Spadiut, O. (2022, March 29). Waste-to-Value: Cultivating Chlorella vulgaris in hemicellulosic hydrolysates from wheat straw [Poster Presentation]. 7th BioProScale Symposium 2022, Berlin, Germany. ( reposiTUm)

Kriechbaum, R., Kopp, J., & Spadiut, O. (2022, September 8). Waste-to-Value: Das Potential von Lebensmittelabfällen für die Mikroalgenkultivierung [Conference Presentation]. Netzwerk Algen 2022: Algen in der Kreislaufwirtschaft, Bundesministerium für Klimaschutz, Umwelt, Energie, Mobilität, Innovation und Technologie; Abt. Energie u. Umwelttechnologien, Wien, Austria. ( reposiTUm)

Kriechbaum, R., & Spadiut, O. (2022, August 30). Waste-to-Value: Das Potential von Lebensmittelabfällen für die Mikroalgenkultivierung [Presentation]. Think Tank WKO, Wien, Austria. ( reposiTUm)

Kriechbaum, R., Serna Loaiza, S., Kopp, J., & Spadiut, O. (2022, December 13). Potential of Lignocellulosic Waste as Substrate for Microalgal Cultivation [Conference Presentation]. Algaeurope 2022, Rom, Italy. ( reposiTUm)

Akhgar, C. K., Ebner, J., Spadiut, O., Schwaighofer, A., & Lendl, B. (2022, January 22). Laser-Based Mid-Infrared Spectroscopy Enables In-line Detection of Protein  Secondary Structure from Preparative Liquid Chromatography [Poster Presentation]. Photonics West 2022, United States of America (the). ( reposiTUm)

Besleaga, M., Ebner, K., Bürgler, M., glieder, anton, Spadiut, O., & Kopp, J. (2022, November). Bi-directional promoter systems facilitate expression of unspecific peroxygenase in K. phaffii (known as P. pastoris) BSYBG11 [Poster Presentation]. European Summit of Industrial Biotechnlogy, Graz, Austria. http://hdl.handle.net/20.500.12708/137085 ( reposiTUm)

Akhgar, C. K., Ebner, J., Alcaraz, M. R., Kopp, J., Goicoechea, H., Spadiut, O., Schwaighofer, A., & Lendl, B. (2022, May 18). Hyphenation of Preparative Liquid Chromatography to Laser-Based Mid-Infrared Spectroscopy for Monitoring of Proteins in Chromatographic Effluents [Poster Presentation]. 17th International Symposium on Hyphenated Techniques in Chromatography and Separation Technology, Ghent, Belgium. https://doi.org/10.34726/3728 ( reposiTUm)

Akhgar, C. K., Ebner, J., Alcaraz, M. R., Kopp, J., Goicoechea, H., Spadiut, O., Schwaighofer, A., & Lendl, B. (2022, May 13). Application of Laser-Based Mid-Infrared Spectroscopy for Inline Monitoring of Proteins from Preparative Liquid Chromatography [Conference Presentation]. Junganalytiker*innenforum 2022, Tulln, Austria. http://hdl.handle.net/20.500.12708/152323 ( reposiTUm)

Schwaighofer, A., Akhgar, C. K., Ebner, J., Alcaraz, M. R., Kopp, J., Goicoechea, H., Spadiut, O., & Lendl, B. (2022, June 23). Hyphenation of Preparative Liquid Chromatography to Laser-Based Mid-IR Spectroscopy for Monitoring of Proteins in Chromatographic Effluents [Poster Presentation]. Analytica 2022, München, Germany. http://hdl.handle.net/20.500.12708/152536 ( reposiTUm)

Rastädter, K., Tramontano, A., Wurm, D. J., Spadiut, O., & Quehenberger, J. (2022, March 29). Dead or alive: a novel PAT tool for the extremophile Sulfolobus acidocaldarius [Conference Presentation]. 7th BioProScale Symposium 2022, Germany. http://hdl.handle.net/20.500.12708/152493 ( reposiTUm)

Rastädter, K., Tramontano, A., Wurm, D. J., Spadiut, O., & Quehenberger, J. (2022, September 21). Flow cytometry-based viability staining for bioprocess monitoring of Sulfolobus acidocaldarius [Poster Presentation]. Extremophiles 2022, Greece. http://hdl.handle.net/20.500.12708/152753 ( reposiTUm)

Spadiut, O. (2021). Extracellular protein production with E. coli - how can it be done and what does it really bring for the DSP? Bioprocessing Summit Europe 2021, Barcelona, Spanien, Spain. http://hdl.handle.net/20.500.12708/101642 ( reposiTUm)

Spadiut, O. (2021). NovoArc - Health without needles. Biovaria, München, Deutschland, Germany. http://hdl.handle.net/20.500.12708/101643 ( reposiTUm)

Spadiut, O., & Kronberger, D. (2020). Inclusion Body Processing: A REAL Black Box Case Study. 12#^{th} Annual PEGS Europe Virtual 2020 (Online Conference), Lissabon, Portugal. http://hdl.handle.net/20.500.12708/101482 ( reposiTUm)

Wurm, D. J., & Spadiut, O. (2019). Shedding more Light on Production and Processing of Inclusion Bodies from E.coli. BioProduction 2019, Frankfurt, Germany. http://hdl.handle.net/20.500.12708/101238 ( reposiTUm)

Hausjell, J., & Spadiut, O. (2019). Challenge accepted: Recombinant production of a hard-to-express membrane-bound cytochrome P450 in yeast. RPP10 Conference - A Comparative View on Host Physiology, Kreta, Greece. http://hdl.handle.net/20.500.12708/101240 ( reposiTUm)

Quehenberger, J., Wurm, D. J., & Spadiut, O. (2019). NovoSome - We will replace 20% of all injections by pills. ESIB 2019 - European summit of industrial biotechnology, Graz, Austria. http://hdl.handle.net/20.500.12708/101226 ( reposiTUm)

Wurm, D. J., Pekarsky, A., Ehmsen, J., & Spadiut, O. (2019). The time has come - indtroducing QbD into inclusion body refolding processes. RPP10 Conference - A Comparative View on Host Physiology, Kreta, Greece. http://hdl.handle.net/20.500.12708/101225 ( reposiTUm)

Spadiut, O. (2019). A tricky endeavour: production of membrane-bound P450s. In https://www.pegsummiteurope.com/protein-purification-technologies (p. 1). http://hdl.handle.net/20.500.12708/50582 ( reposiTUm)

Spadiut, O. (2018). Continuous Bioprocessing - how can it be done? ZETA Symposium 2018, Leibnitz, Austria. http://hdl.handle.net/20.500.12708/100755 ( reposiTUm)

Hausjell, J., Weissensteiner, J., Halbwirth, H., & Spadiut, O. (2018). Challenges in the Recombinant Production of Eukaryotic Cytochrome P450s in microbial cell factories [Poster Presentation]. 2. http://hdl.handle.net/20.500.12708/50311 ( reposiTUm)

Kastenhofer, J., Wurm, D. J., Mairhofer, G., Striedner, G., & Spadiut, O. (2018). A growth decoupled E. coli expression system allows high-yield recombinant production of antibody fragments. BioProduction Congress 2018, Dublin, Ireland. http://hdl.handle.net/20.500.12708/100821 ( reposiTUm)

Pekarsky, A., Eggenreich, B., Wurm, D. J., & Spadiut, O. (2018). A success story - lnclusion bodies are more than molecular waste. BioProduction Congress 2018, Dublin, Ireland. http://hdl.handle.net/20.500.12708/100820 ( reposiTUm)

Spadiut, O. (2018). Inclusion bodies - more than just waste! EuroSciCon Joint Event on Biotechnology, Stem Cell and Molecular Diagnostics, Amsterdam, Netherlands (the). http://hdl.handle.net/20.500.12708/100754 ( reposiTUm)

Spadiut, O. (2018). Chormatogram fingerprinting to follow integrated bioprocesses. World Advanced Therapies & Regenerative Medicine 2018, London, United Kingdom of Great Britain and Northern Ireland (the). http://hdl.handle.net/20.500.12708/100753 ( reposiTUm)

Slouka, C., Spadiut, O., Wurm, D. J., & Kopp, J. (2018). Enabling continuous upstream bioprocessing using tunable promoters and model predictive control. World Biopharm Forum 2018, Oxford, United Kingdom of Great Britain and Northern Ireland (the). http://hdl.handle.net/20.500.12708/100730 ( reposiTUm)

Spadiut, O., & Pittermann, B. (2017). Understanding Freeze & Thaw Processes: Safer Storage and Transportation of High-Quality Proteins as Keys to Process Validation. ZETA Symposium, Graz, Austria. http://hdl.handle.net/20.500.12708/100408 ( reposiTUm)

Spadiut, O. (2017). How Induction Impacts Inclusion Body Properties and Inlcusion Body Processing in E. coli. 14#^{th} International Life Science Meeting, Krems, Austria. http://hdl.handle.net/20.500.12708/100299 ( reposiTUm)

Spadiut, O. (2017). A novel toolbox for monitoring inclusion body processing. Cell Culture & Downstream Processing World Congress 2017, München, Germany. http://hdl.handle.net/20.500.12708/100276 ( reposiTUm)

Spadiut, O. (2017). Can a novel monitoring tool based on chromatogram fingerprinting help in enabling continuous bioprocessing? 10#^{th} Annual Biolnnovation Leaders Summit GBX Summits, Berlin, Germany. http://hdl.handle.net/20.500.12708/100277 ( reposiTUm)

Spadiut, O. (2017). How to tune recombinant protein production in E. coli for enhanced production of biopharmaceuticals. 15#^{th} World Congress on Biotechnology and Biotech Industries Meet, Rom, Italy. http://hdl.handle.net/20.500.12708/100291 ( reposiTUm)

Hausjell, J., Weissensteiner, J., Spadiut, O., & Halbwirth, H. (2017). Challenges in the Recombinant Production of P450s in Yeast. 20#^{th} International Conference on Cytochrome P450, Düsseldorf, Germany. http://hdl.handle.net/20.500.12708/100538 ( reposiTUm)

Weissensteiner, J., Roth, B. L., Hausjell, J., Molitor, C., Spadiut, O., & Halbwirth, H. (2017). Functional Expression of F3’H and Ch3H Provides Insights in their Differing Substrate Specificity. 20#^{th} International Conference on Cytochrome P450, Düsseldorf, Germany. http://hdl.handle.net/20.500.12708/100539 ( reposiTUm)

Wurm, D. J., Eggenreich, B., Herwig, C., & Spadiut, O. (2017). Controlled Refolding of Inclusion Body Protein to Boost Product Yields. BioProduction Congress 2017, Dublin, Ireland. http://hdl.handle.net/20.500.12708/100555 ( reposiTUm)

Spadiut, O. (2017). How Induction Impacts Inclusion Body Properties and Inclusion Body Processing in E. coli. PEGS Boston, Boston, United States of America (the). http://hdl.handle.net/20.500.12708/100311 ( reposiTUm)

Spadiut, O. (2017). A novel monitoring tool based on chromatogram fingerprinting as potential enabler of continuous bioprocessing. Biotech 2017, Wädenswill, Switzerland. http://hdl.handle.net/20.500.12708/100409 ( reposiTUm)

Spadiut, O. (2017). The production of a novel scFv against coeliac disease - from gene to final product. European Antibody Congress 2017, Basel, Switzerland. http://hdl.handle.net/20.500.12708/100410 ( reposiTUm)

Spadiut, O. (2016). Continuous Bioprocessing - status quo and challenges. 1. European Antibody Congress, Basel, Switzerland. http://hdl.handle.net/20.500.12708/100027 ( reposiTUm)

Spadiut, O. (2016). A novel tandem Fab against coeliac disease. 1. European Antibody Congress, Basel, Switzerland. http://hdl.handle.net/20.500.12708/100028 ( reposiTUm)

Spadiut, O. (2016). Identification of interaction effects between unit operations. Workshop on Methods for Accelerating Scalable Bioprocess Development, Wien, Austria. http://hdl.handle.net/20.500.12708/100030 ( reposiTUm)

Eggenreich, B., Rajamanickam, V., Herwig, C., & Spadiut, O. (2016). A fast approach to monitor inclusion body downstream processing steps of a Dietary scFv as a possible treatment of celiac disease. 1. European Antibody Congress, Basel, Switzerland. http://hdl.handle.net/20.500.12708/100045 ( reposiTUm)

Spadiut, O. (2016). Horseradish Peroxidase - From Genome to Protein. XI Meeting of young Chemical Engineers, Zagreb, Croatia. http://hdl.handle.net/20.500.12708/100029 ( reposiTUm)

Eggenreich, B., Rajamanickam, V., Spadiut, O., & Herwig, C. (2016). A Novel PAT Tool To Monitor The lmpurity Pattern During lnclusion Body Processing. In http://www.esbes2016.org/ (p. 1). http://hdl.handle.net/20.500.12708/49406 ( reposiTUm)

Rajamanickam, V., Spadiut, O., & Herwig, C. (2015). Implementation of monolith chromatography for purification of recombinant glycoproteins expressed in yeast. Biopartitioning & Purification Conference 2015, Wien, Austria. http://hdl.handle.net/20.500.12708/99715 ( reposiTUm)

Spadiut, O. (2015). Horseradish Peroxidase - from Genome to Protein. 12#^{th} International Life Science Meeting, Krems, Austria. http://hdl.handle.net/20.500.12708/99878 ( reposiTUm)

Ullmann, E.-M., Tan, T.-C., Gundinger, T., Herwig, C., Divne, C., & Spadiut, O. (2015). A novel cytosolic NADH: Quinone oxidreductase from Methanothermobacter marburgensis. Biotrans 2015, Wien, Austria. http://hdl.handle.net/20.500.12708/99877 ( reposiTUm)

Spadiut, O. (2015). Monoliths as PAT tools for bioprocess improvement. PEGS Europe 2015, Lissabon, Portugal. http://hdl.handle.net/20.500.12708/99851 ( reposiTUm)

Capone, S., & Spadiut, O. (2015). Development of a mixed feed strategy for a recombinant Pichia pastoris strain producing with a de-repression promoter. Bioprocessing Summit 2015, Boston, United States of America (the). http://hdl.handle.net/20.500.12708/99876 ( reposiTUm)

Spadiut, O. (2014). Efficient DSP for hyperglycosylated proteins from yeast. BioProduction 2014, Barcelona, Spain. http://hdl.handle.net/20.500.12708/99449 ( reposiTUm)

Spadiut, O. (2014). Purification and biochemical characterization of 19 recombinant plant peroxidase isoenzymes produced in Pichia pastoris. Monolith Summer School & Symposium 2014, Portoroz, Slovenia. http://hdl.handle.net/20.500.12708/99445 ( reposiTUm)

Dietzsch, C., Spadiut, O., & Herwig, C. (2012). A novel on-line monitoring device for fast and quantitative bioprocess development. 15#^{th} European Congress on Biotechnology, Istanbul, Türkei, Non-EU. http://hdl.handle.net/20.500.12708/98797 ( reposiTUm)

Spadiut, O. (2012). Efficient purification of a recombinant plant peroxidase by a mixed-mode resin. 15#^{th} European Congress on Biotechnology, Istanbul, Türkei, Non-EU. http://hdl.handle.net/20.500.12708/98798 ( reposiTUm)

Dietzsch, C., Spadiut, O., & Herwig, C. (2011). A dynamic method based on the specific substrate uptake rate to set up a feeding strategy for Pichia pastoris. Bio Production Forum, Ulm, Deutschland, EU. http://hdl.handle.net/20.500.12708/98539 ( reposiTUm)

Spadiut, O., & Herwig, C. (2010). Erzeugung und gegenwärtige Abfüllungs- und Einfriertechnologie von Proteinlösungen aus biotechnologischer Erzeugung. http://hdl.handle.net/20.500.12708/36719 ( reposiTUm)

Spadiut, O., & Herwig, C. (2010). Schädigungsmechanismen von Proteinen. http://hdl.handle.net/20.500.12708/36720 ( reposiTUm)

Spadiut, O., & Herwig, C. (2010). Analyse Proteinstabilität durch Pufferkomponenten. http://hdl.handle.net/20.500.12708/36721 ( reposiTUm)

Spadiut, O. (2014). Horseradish peroxidase - from genome to protein [Professorial Dissertation, Technische Universität Wien]. reposiTUm. http://hdl.handle.net/20.500.12708/159455 ( reposiTUm)