<div class="csl-bib-body">
<div class="csl-entry">Li, Z., Torgersen, J., Ajami, A., Mühleder, S., Qin, X., Husinsky, W., Holnthoner, W., Ovsianikov, A., Stampfl, J., & Liska, R. (2013). Initiation efficiency and cytotoxicity of novel water-soluble two-photon photoinitiators for direct 3D microfabrication of hydrogels. <i>RSC Advances</i>. https://doi.org/10.1039/c3ra42918k</div>
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The final publication is available via <a href="https://doi.org/10.1039/c3ra42918k" target="_blank">https://doi.org/10.1039/c3ra42918k</a>.
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dc.description.abstract
The lack of efficient water-soluble two-photon absorption (TPA) photoinitiators has been a critical obstruction for three dimensional hydrogel microfabrications with high water load by two-photon induced polymerization (TPIP). In this paper, a series of cyclic 10 benzylidene ketone-based two-photon initiators, containing carboxylic acid sodium salts to improve water solubility, were synthesized via classical aldol condensation reactions. Cytotoxicity of cyclopentanone-based photoinitiators is as low as that of the well-known biocompatible photoinitiator Irgacure 2959 as assessed in the dark with MG63 cell line. In z-scan measurement, the TPA cross sections of the investigated initiators are only moderate in water, while the TPA values for hydrophobic analogues measured in chloroform were much higher. All novel initiators exhibited broad processing windows in TPIP tests using hydrophilic photopolymers with up to 50 wt% 15 of water. Impressively, microfabrication of hydrogels with excellent precision was possible at a writing speed as high as 100 mm/s.
en
dc.language
English
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dc.language.iso
en
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dc.publisher
The Royal Society of Chemistry
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dc.relation.ispartof
RSC Advances
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dc.rights.uri
http://rightsstatements.org/vocab/InC/1.0/
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dc.title
Initiation efficiency and cytotoxicity of novel water-soluble two-photon photoinitiators for direct 3D microfabrication of hydrogels
en
dc.type
Article
en
dc.type
Artikel
de
dc.rights.license
Urheberrechtsschutz
de
dc.rights.license
In Copyright
en
dc.contributor.affiliation
TU Wien, Österreich
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dc.contributor.affiliation
AUVA Research Centre, Ludwig Boltzmann Institute for Experimental and Clinical Traumatology, Austria
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dc.contributor.affiliation
AUVA Research Centre, Ludwig Boltzmann Institute for Experimental and Clinical Traumatology, Austria
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dc.rights.holder
The Royal Society of Chemistry
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dc.type.category
Original Research Article
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tuw.journal.peerreviewed
true
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tuw.peerreviewed
true
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tuw.version
am
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dcterms.isPartOf.title
RSC Advances
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tuw.publication.orgunit
E308 - Institut für Werkstoffwissenschaft und Werkstofftechnologie
-
tuw.publication.orgunit
E311 - Institut für Fertigungstechnik und Photonische Technologien
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tuw.publication.orgunit
E134 - Institut für Angewandte Physik
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tuw.publisher.doi
10.1039/c3ra42918k
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dc.identifier.eissn
2046-2069
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dc.identifier.libraryid
AC11359639
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dc.identifier.urn
urn:nbn:at:at-ubtuw:3-1122
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tuw.author.orcid
0000-0001-5845-8653
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tuw.author.orcid
0000-0001-6287-2216
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tuw.author.orcid
0000-0001-6425-9028
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tuw.author.orcid
0000-0001-5846-0198
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tuw.author.orcid
0000-0002-3626-5647
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tuw.author.orcid
0000-0001-7865-1936
-
dc.rights.identifier
Urheberrechtsschutz
de
dc.rights.identifier
In Copyright
en
wb.sci
true
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item.grantfulltext
open
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item.openairetype
research article
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item.fulltext
with Fulltext
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item.languageiso639-1
en
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item.openairecristype
http://purl.org/coar/resource_type/c_2df8fbb1
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item.openaccessfulltext
Open Access
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item.cerifentitytype
Publications
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application/pdf
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crisitem.author.dept
TU Wien
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crisitem.author.dept
E311 - Institut für Fertigungstechnik und Photonische Technologien
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crisitem.author.dept
E134 - Institut für Angewandte Physik
-
crisitem.author.dept
AUVA Research Centre, Ludwig Boltzmann Institute for Experimental and Clinical Traumatology, Austria
-
crisitem.author.dept
E134 - Institut für Angewandte Physik
-
crisitem.author.dept
AUVA Research Centre, Ludwig Boltzmann Institute for Experimental and Clinical Traumatology, Austria
-
crisitem.author.dept
E308-02-3 - Forschungsgruppe 3D Printing and Biofabrication
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crisitem.author.dept
E308-02 - Forschungsbereich Polymer- und Verbundwerkstoffe