DC FieldValueLanguage
dc.contributor.advisorGilbert, Rénald-
dc.contributor.authorKastberger, Birgit-
dc.date.accessioned2020-06-30T11:39:56Z-
dc.date.issued2011-
dc.date.submitted2011-02-
dc.identifier.urihttps://resolver.obvsg.at/urn:nbn:at:at-ubtuw:1-42163-
dc.identifier.urihttp://hdl.handle.net/20.500.12708/12301-
dc.description.abstractFor my Master Thesis project I was charged with the design of two recombinant types of adenoviruses. The first adenovirus should possess a K-coil sequence situated in the HI-loop region of the fibre's knob domain, the other one was supposed to have an ablated CAR tropism in addition to the identical K-coil insertion. The virus' transduction efficiency via EGF-receptors was monitored by fluorescents provoked by a GFP marker, that had to be inserted into the E1 region of the AdV genome for this reason.en
dc.formatii, 91 S.-
dc.languageEnglish-
dc.language.isoen-
dc.subjectAdenovirusde
dc.subjectGentherapiede
dc.subjectK-Coilde
dc.subjectE-Coil Technologiede
dc.subjectKrebsde
dc.subjectBiotechnologiede
dc.subjectTropismusde
dc.subjectCar-Rezeptorde
dc.subjectGFP-Markerde
dc.subjectAdenovirusen
dc.subjectGene therapyen
dc.subjectK-Coilen
dc.subjectE-Coil Technologyen
dc.subjectCanceren
dc.subjectBiotechnologyen
dc.subjectTropismen
dc.subjectCar-Receptoren
dc.subjectGFP-Markeren
dc.titleCreating universality for cancer gene therapy in applying Adenovirus vectors with altered tropism : designing Adenovirus particles using K-Coil/E-Coil technology to control receptor specificityen
dc.typeThesisen
dc.typeHochschulschriftde
dc.contributor.assistantKubicek, Peter Christian-
tuw.publication.orgunitE166 - Institut für Verfahrenstechnik, Umwelttechnik und Technische Biowissenschaften-
dc.type.qualificationlevelDiploma-
dc.identifier.libraryidAC07809229-
dc.description.numberOfPages91-
dc.identifier.urnurn:nbn:at:at-ubtuw:1-42163-
dc.thesistypeDiplomarbeitde
dc.thesistypeDiploma Thesisen
item.fulltextwith Fulltext-
item.openairetypeThesis-
item.openairetypeHochschulschrift-
item.cerifentitytypePublications-
item.cerifentitytypePublications-
item.languageiso639-1en-
item.grantfulltextopen-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
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