<div class="csl-bib-body">
<div class="csl-entry">Ghodrati, M., Schlöglhofer, T., Maurer, A., Khienwad, T., Zimpfer, D., Beitzke, D., Zonta, F., Moscato, F., Schima, H., & Aigner, P. (2022). Effects of the atrium on intraventricular flow patterns during mechanical circulatory support. <i>International Journal of Artificial Organs</i>, <i>45</i>(4), 421–430. https://doi.org/10.1177/03913988211056018</div>
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dc.identifier.issn
0391-3988
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dc.identifier.uri
http://hdl.handle.net/20.500.12708/138597
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dc.description.abstract
Simulations of the ventricular flow patterns during left ventricular assist device (LVAD) support are mainly performed with idealized cylindrical inflow, neglecting the influence of the atrial vortex. In this study, the influence of the left atrium (LA) on the intra-ventricular flow was investigated via Computational Fluid Dynamics (CFD) simulations. Ventricular flow was simulated by a combined Eulerian (carrier flow)/Lagrangian (particles) approach taking into account either the LA or a cylindrical inflow section to mimic a fully support condition. The flow deviation at the mitral valve, the blood low-velocity volume as well as the residence time and shear stress history of the particles were calculated. Inclusion of the LA deflects the flow at the mitral valve by 25°, resulting in an asymmetric flow jet entering the left ventricle. This reduced the ventricular low-velocity volume by 40% (from 6.4 to 3.9 cm³), increased (40%) the shear stress experienced by particles and correspondingly increased (27%) their residence time. Under the studied conditions, the atrial geometry plays a major role in the development of intraventricular flow patterns. A reliable prediction of blood flow dynamics and consequently thrombosis risk analysis within the ventricle requires the consideration of the LA in computational simulations.
en
dc.language.iso
en
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dc.publisher
SAGE PUBLICATIONS LTD
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dc.relation.ispartof
International Journal of Artificial Organs
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dc.subject
General Medicine
en
dc.subject
Biomedical Engineering
en
dc.subject
Bioengineering
en
dc.subject
Biomaterials
en
dc.subject
Medicine
en
dc.title
Effects of the atrium on intraventricular flow patterns during mechanical circulatory support
en
dc.type
Artikel
de
dc.type
Article
en
dc.description.startpage
421
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dc.description.endpage
430
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dc.type.category
Original Research Article
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tuw.container.volume
45
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tuw.container.issue
4
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tuw.journal.peerreviewed
true
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tuw.peerreviewed
true
-
tuw.researchTopic.id
C2
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tuw.researchTopic.name
Computational Fluid Dynamics
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tuw.researchTopic.value
100
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dcterms.isPartOf.title
International Journal of Artificial Organs
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tuw.publication.orgunit
E322-01 - Forschungsbereich Strömungsmechanik
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tuw.publisher.doi
10.1177/03913988211056018
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dc.date.onlinefirst
2021-10-29
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dc.identifier.eissn
1724-6040
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dc.description.numberOfPages
10
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tuw.author.orcid
0000-0003-3179-3827
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tuw.author.orcid
0000-0002-3212-2112
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wb.sci
true
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wb.sciencebranch
Medizinische Biotechnologie
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wb.sciencebranch
Physik, Astronomie
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wb.sciencebranch.oefos
3040
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wb.sciencebranch.oefos
1030
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wb.facultyfocus
Numerische Ingenieursmethoden und IT gestütztes Engineering
de
wb.facultyfocus
Numerische Ingenieursmethoden und IT gestütztes Engineering
en
wb.facultyfocus.faculty
E300
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item.openairetype
research article
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item.fulltext
no Fulltext
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item.openairecristype
http://purl.org/coar/resource_type/c_2df8fbb1
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item.grantfulltext
none
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item.cerifentitytype
Publications
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item.languageiso639-1
en
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crisitem.author.dept
E322-01 - Forschungsbereich Strömungsmechanik
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crisitem.author.parentorg
E322 - Institut für Strömungsmechanik und Wärmeübertragung