<div class="csl-bib-body">
<div class="csl-entry">Kopp, J., Bayer, B., Slouka, C., Striedner, G., Dürkop, M., & Spadiut, O. (2022). Fundamental insights in early-stage inclusion body formation. <i>Microbial Biotechnology</i>, <i>00</i>. https://doi.org/10.1111/1751-7915.14117</div>
</div>
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dc.identifier.issn
1751-7915
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dc.identifier.uri
http://hdl.handle.net/20.500.12708/139918
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dc.description.abstract
Early-stage inclusion body formation is still mysterious. Literature is ambiguous about the existence of rod-shaped protein aggregates, a potential sponge-like inclusion body scaffold as well as the number of inclusion bodies per Escherichia coli cell. In this study, we verified the existence of rod-shaped inclusion bodies, confirmed their porous morphology, the presence of multiple protein aggregates per cell and modelled inclusion body formation as function of the number of generations.
en
dc.language.iso
en
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dc.publisher
WILEY
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dc.relation.ispartof
Microbial Biotechnology
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dc.subject
Escherichia coli
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dc.subject
rod-shaped inclusion body,
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dc.subject
inclusion body morphology
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dc.subject
inclusion body scaffold
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dc.subject
cell doubling
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dc.subject
microscopy
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dc.title
Fundamental insights in early-stage inclusion body formation