<div class="csl-bib-body">
<div class="csl-entry">Desoeuvres, A., Szmolyan, P., & Radulescu, O. (2022). Qualitative Dynamics of Chemical Reaction Networks: An Investigation Using Partial Tropical Equilibrations. In Petre Ion & Păun Andrei (Eds.), <i>Computational Methods in Systems Biology</i> (pp. 61–85). Springer Cham. https://doi.org/10.1007/978-3-031-15034-0_4</div>
</div>
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dc.identifier.uri
http://hdl.handle.net/20.500.12708/139921
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dc.description.abstract
We discuss a method to describe the qualitative dynamics of chemical reaction networks in terms of symbolic dynamics. The method, that can be applied to mass-action reaction networks with separated timescales, uses solutions of the partial tropical equilibration problem as proxies for symbolic states. The partial tropical equilibration solutions are found algorithmically. These solutions also provide the scaling needed for slow-fast decomposition and model reduction. Any trace of the model can thus be represented as a sequence of local approximations of the full model. We illustrate the method using as case study a biochemical model of the cell cycle.
en
dc.language.iso
en
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dc.relation.ispartofseries
Lecture Notes in Computer Science
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dc.subject
chemical reaction networks
en
dc.subject
dimension reduction
en
dc.subject
time scale separation
en
dc.subject
tropical equilibration
en
dc.subject
slow manifolds
en
dc.subject
cell cycle
en
dc.title
Qualitative Dynamics of Chemical Reaction Networks: An Investigation Using Partial Tropical Equilibrations
en
dc.type
Inproceedings
en
dc.type
Konferenzbeitrag
de
dc.contributor.affiliation
Université de Montpellier, France
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dc.relation.isbn
978-3-031-15034-0
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dc.relation.doi
10.1007/978-3-031-15034-0
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dc.relation.issn
0302-9743
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dc.description.startpage
61
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dc.description.endpage
85
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dc.type.category
Full-Paper Contribution
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dc.relation.eissn
1611-3349
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tuw.booktitle
Computational Methods in Systems Biology
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tuw.container.volume
13447
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tuw.relation.publisher
Springer Cham
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tuw.publication.invited
invited
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tuw.researchTopic.id
C4
-
tuw.researchTopic.id
C6
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tuw.researchTopic.name
Mathematical and Algorithmic Foundations
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tuw.researchTopic.name
Modeling and Simulation
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tuw.researchTopic.value
60
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tuw.researchTopic.value
40
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tuw.publication.orgunit
E101-01 - Forschungsbereich Analysis
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tuw.publisher.doi
10.1007/978-3-031-15034-0_4
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dc.description.numberOfPages
25
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tuw.author.orcid
0000-0003-1556-0513
-
tuw.author.orcid
0000-0001-6453-5707
-
tuw.editor.orcid
0000-0002-5014-5529
-
tuw.editor.orcid
0000-0002-1644-8198
-
tuw.event.name
20th International Conference on Computational Methods in Systems Biology (CMSB 2022)
en
dc.description.sponsorshipexternal
ANR agence nationale de la recherche
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dc.description.sponsorshipexternal
Campus France/BMBWF Program Amadeus 2020
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dc.relation.grantnoexternal
ANR-17-CE40-0036
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tuw.event.startdate
14-09-2022
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tuw.event.enddate
16-09-2022
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tuw.event.online
On Site
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tuw.event.type
Event for scientific audience
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tuw.event.place
Bucharest
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tuw.event.country
RO
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tuw.event.presenter
Desoeuvres, Aurélien
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wb.sciencebranch
Mathematik
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wb.sciencebranch.oefos
1010
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wb.sciencebranch.value
100
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item.cerifentitytype
Publications
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item.fulltext
no Fulltext
-
item.languageiso639-1
en
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item.openairetype
conference paper
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item.openairecristype
http://purl.org/coar/resource_type/c_5794
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item.grantfulltext
none
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crisitem.author.dept
E101-01 - Forschungsbereich Analysis
-
crisitem.author.dept
Universit� de Montpellier
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crisitem.author.orcid
0000-0003-1556-0513
-
crisitem.author.orcid
0000-0001-6453-5707
-
crisitem.author.parentorg
E101 - Institut für Analysis und Scientific Computing
