<div class="csl-bib-body">
<div class="csl-entry">Chachques, J. C., Mazzini, L., Mitrecic, D., Hellmich, C., Zavan, B., Rogante, M., Latremouille, C., & Rustichelli, F. (2020). Covid-19 Pandemic: Cardiovascular and Neurologic Im-pact, Early Signs and Symptoms. <i>American Journal of Biomedical Science & Research</i>, <i>11</i>(1), 51–63. https://doi.org/10.34297/ajbsr.2020.11.001586</div>
</div>
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dc.identifier.uri
http://hdl.handle.net/20.500.12708/141214
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dc.description.abstract
Background: Scientists and physicians continue their cutting-edge work on bacteria, parasites and viruses, responsible for 17 million deaths
each year worldwide. The purpose of this article is to review our clinical experience with COVID-19 patients observed in the Cardiovascular Division
of Pompidou Hospital (University of Paris, France) and the Department of Neurology of the Eastern Piedmont University (Novara, Italy), related
with the impact on the cardiovascular, hematologic, neurologic systems and sense organs. Mathematical modeling for pandemic spreading control
(protection versus hazards), proposed by Vienna University of Technology (Austria), are analyzed.
Methods: We sought to characterize the cardiovascular and neurologic manifestations, in patients with Covid-19. Special attention was given
to initial signs and symptoms in order to facilitate early diagnosis and therapy. Indications of ECMO membrane oxygenation for cardio-respiratory
support are evaluated, mathematical models for control pandemic spreading are described.
Results: Early neuro-sensorial symptoms like anosmia and dysgeusia are useful for diagnostic, patient’s isolation, and treatment. Angio-
hematologic acro-ischemia syndrome and dermatological signs are mostly related with immune dysregulation, neoangiogenesis, vasculitis, and
vessel thrombosis resulting from “cytokine storm syndrome”. Acro-ischemia syndrome allows diagnosis and early treatment of disseminated
intravascular coagulation, with mortality risks for children and adults.
Conclusion: Covid-19 is a prothrombotic disease with a unique global lethality. Strong inflammatory response to viral infection severely affects
cardiovascular, and neurologic systems, as well as respiratory, immune and hematologic systems. Fast identification of acro-ischemia syndrome
permits the care of disseminated intravascular coagulation complications. Early symptoms like gustatory and olfactory loss are useful for Covid
diagnostic. Mathematical models play a significant role in the understanding of COVID-19 transmission mechanisms, structures, and features. It
should be of interest for policymakers and for explaining recurrent epidemic outbreaks.
en
dc.language.iso
en
-
dc.publisher
BiomedGrid LLC
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dc.relation.ispartof
American Journal of biomedical science & research
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dc.subject
Immunology
en
dc.subject
Microbiology (medical)
en
dc.subject
Immunology and Allergy
en
dc.title
Covid-19 Pandemic: Cardiovascular and Neurologic Im-pact, Early Signs and Symptoms
en
dc.type
Artikel
de
dc.type
Article
en
dc.contributor.affiliation
Cardiovascular Division, Pompidou Hospital, France
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dc.contributor.affiliation
Department of Neurology, Maggiore della Carità Hospital, Italy
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dc.contributor.affiliation
Croatian Institute for Brain Research, School of Medicine University of Zagreb, Croatia
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dc.contributor.affiliation
Department of Medical Sciences, University of Ferrara, Italy
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dc.contributor.affiliation
Rogante Engineering Office, Italy
-
dc.contributor.affiliation
Cardiovascular Division, Pompidou Hospital, France
-
dc.contributor.affiliation
Physical Sciences Division, Polytechnic University of Ancona-Marche, Italy
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dc.description.startpage
51
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dc.description.endpage
63
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dc.type.category
Original Research Article
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tuw.container.volume
11
-
tuw.container.issue
1
-
tuw.peerreviewed
false
-
tuw.researchTopic.id
C6
-
tuw.researchTopic.name
Modelling and Simulation
-
tuw.researchTopic.value
100
-
dcterms.isPartOf.title
American Journal of biomedical science & research
-
tuw.publication.orgunit
E202-01 - Forschungsbereich Festigkeitslehre und Biomechanik
-
tuw.publisher.doi
10.34297/ajbsr.2020.11.001586
-
dc.identifier.eissn
2642-1747
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dc.description.numberOfPages
13
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wb.sciencebranch
Bauingenieurwesen
-
wb.sciencebranch
Physik, Astronomie
-
wb.sciencebranch.oefos
2011
-
wb.sciencebranch.oefos
1030
-
wb.facultyfocus
Materialwissenschaften
de
wb.facultyfocus
Building Materials
en
wb.facultyfocus.faculty
E200
-
item.fulltext
no Fulltext
-
item.grantfulltext
none
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item.openairetype
research article
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item.openairecristype
http://purl.org/coar/resource_type/c_2df8fbb1
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item.languageiso639-1
en
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item.cerifentitytype
Publications
-
crisitem.author.dept
Cardiovascular Division, Pompidou Hospital, France
-
crisitem.author.dept
Department of Neurology, Maggiore della Carità Hospital, Italy
-
crisitem.author.dept
Croatian Institute for Brain Research, School of Medicine University of Zagreb, Croatia
-
crisitem.author.dept
E202 - Institut für Mechanik der Werkstoffe und Strukturen
-
crisitem.author.dept
Department of Medical Sciences, University of Ferrara, Italy
-
crisitem.author.dept
Rogante Engineering Office, Italy
-
crisitem.author.dept
Cardiovascular Division, Pompidou Hospital, France
-
crisitem.author.dept
Physical Sciences Division, Polytechnic University of Ancona-Marche, Italy