<div class="csl-bib-body">
<div class="csl-entry">Schönbauer, D., Lukas, F., & Schnürch, M. (2019). Toluene and its Derivatives as Atom-Efficient Benzylating Agents for Secondary Amines. <i>SYNLETT</i>, <i>30</i>(01), 94–98. https://doi.org/10.1055/s-0037-1610342</div>
</div>
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dc.identifier.issn
0936-5214
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dc.identifier.uri
http://hdl.handle.net/20.500.12708/142423
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dc.description.abstract
Toluene as a replacement for common N -benzylating agents, such as benzyl bromide, can be an atom-efficient alternative reagent. Under nickel catalysis and mildly oxidative conditions, it is possible to activate toluene efficiently and use it directly for the benzylation of different 2-aminopyridines. The transformation is not restricted to simple toluene, but also substituted derivatives give the desired product in good yields. Effective cleavage of the pyridine moiety is presented.
en
dc.language.iso
en
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dc.publisher
GEORG THIEME VERLAG KG
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dc.relation.ispartof
SYNLETT
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dc.subject
Organic Chemistry
en
dc.subject
c-h functionalization
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dc.subject
benzylation
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dc.subject
nickel catalysis
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dc.subject
toluene activation
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dc.subject
amines
en
dc.title
Toluene and its Derivatives as Atom-Efficient Benzylating Agents for Secondary Amines
en
dc.type
Artikel
de
dc.type
Article
en
dc.description.startpage
94
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dc.description.endpage
98
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dc.type.category
Short/Brief/Rapid Communication
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tuw.container.volume
30
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tuw.container.issue
01
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tuw.journal.peerreviewed
true
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tuw.peerreviewed
true
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tuw.researchTopic.id
X1
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tuw.researchTopic.name
außerhalb der gesamtuniversitären Forschungsschwerpunkte