<div class="csl-bib-body">
<div class="csl-entry">Wieland, K., Tauber, S., Gasser, C., Rettenbacher, L. A., Lux, L., Radel, S., & Lendl, B. (2019). In-Line Ultrasound-Enhanced Raman Spectroscopy Allows for Highly Sensitive Analysis with Improved Selectivity in Suspensions. <i>Analytical Chemistry</i>, <i>91</i>(22), 14231–14238. https://doi.org/10.1021/acs.analchem.9b01105</div>
</div>
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dc.identifier.issn
0003-2700
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dc.identifier.uri
http://hdl.handle.net/20.500.12708/143943
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dc.description.abstract
Raman spectroscopy is a nondestructive characterization method offering chemical-specific information. However, the cross-section of inelastically (Raman) scattered light is very low compared to elastically (Rayleigh) scattered light, resulting in weak signal intensities in Raman spectroscopy. Despite providing crucial information in off-line measurements, it usually is not sensitive enough for efficient, in-line process control in conjunction with low particle concentrations. To overcome this limitation, two custom-made 1.4404 stainlesssteel prototype add-ons were developed for in-line Raman probes that enable ultrasound particle manipulation and thus concentration of particles in suspensions in the focus of the Raman excitation laser. Depending on size and density differences between particles and the carrier medium, particles are typically caught in the nodal planes of a quasi-standing wave field formed in an acoustic resonator in front of the sensor. Two arrangements were realized with regard to the propagation direction of the ultrasonic wave relative to the propagation direction of the laser. The parallel arrangement improved the limit of detection (LOD) by a factor of ≈30. In addition to increased sensitivity, the perpendicular arrangement offers increased selectivity: modifying the frequency of the ultrasonic wave field allows the liquid or solid phase to be moved into the focus of the Raman laser. The combination of in-line Raman spectroscopy with ultrasound particle manipulation holds promise to push the limits of conventional Raman spectroscopy, hence broadening its field of application to areas where previously Raman spectroscopy has not had sufficient sensitivity for accurate, in-line detection.
en
dc.language.iso
en
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dc.relation.ispartof
Analytical Chemistry
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dc.subject
Analytical Chemistry
en
dc.title
In-Line Ultrasound-Enhanced Raman Spectroscopy Allows for Highly Sensitive Analysis with Improved Selectivity in Suspensions
en
dc.type
Artikel
de
dc.type
Article
en
dc.description.startpage
14231
-
dc.description.endpage
14238
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dc.type.category
Original Research Article
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tuw.container.volume
91
-
tuw.container.issue
22
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tuw.journal.peerreviewed
true
-
tuw.peerreviewed
true
-
tuw.researchTopic.id
M2
-
tuw.researchTopic.name
Materials Characterization
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tuw.researchTopic.value
100
-
dcterms.isPartOf.title
Analytical Chemistry
-
tuw.publication.orgunit
E164-02-1 - Forschungsgruppe Prozessanalytik
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tuw.publisher.doi
10.1021/acs.analchem.9b01105
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dc.identifier.eissn
1520-6882
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dc.description.numberOfPages
8
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tuw.author.orcid
0000-0002-4535-5679
-
tuw.author.orcid
0000-0003-3838-5842
-
wb.sci
true
-
wb.sciencebranch
Chemie
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wb.sciencebranch.oefos
1040
-
wb.facultyfocus
Chemistry and Technology of Materials
de
wb.facultyfocus
Chemistry and Technology of Materials
en
wb.facultyfocus.faculty
E150
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item.fulltext
no Fulltext
-
item.openairetype
research article
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item.languageiso639-1
en
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item.grantfulltext
restricted
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item.openairecristype
http://purl.org/coar/resource_type/c_2df8fbb1
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item.cerifentitytype
Publications
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crisitem.author.dept
E164-02-1 - Forschungsgruppe Prozessanalytik
-
crisitem.author.dept
E354-02 - Forschungsbereich Integrated Circuits
-
crisitem.author.dept
TU Wien
-
crisitem.author.dept
E164-02-1 - Forschungsgruppe Prozessanalytik
-
crisitem.author.dept
E134 - Institut für Angewandte Physik
-
crisitem.author.dept
E164-02 - Forschungsbereich Umwelt-, Prozessanalytik und Sensoren
-
crisitem.author.orcid
0000-0003-3838-5842
-
crisitem.author.parentorg
E164-02 - Forschungsbereich Umwelt-, Prozessanalytik und Sensoren
-
crisitem.author.parentorg
E354 - Electrodynamics, Microwave and Circuit Engineering
-
crisitem.author.parentorg
E164-02 - Forschungsbereich Umwelt-, Prozessanalytik und Sensoren
-
crisitem.author.parentorg
E130 - Fakultät für Physik
-
crisitem.author.parentorg
E164 - Institut für Chemische Technologien und Analytik