<div class="csl-bib-body">
<div class="csl-entry">Schaaf, P., Gojic, V., Bayer, T., Rudroff, F., Schnürch, M., & Mihovilovic, M. D. (2018). Easy Access to Enantiopure (S)- and (R)-Aryl Alkyl Alcohols by a Combination of Gold(III)-Catalyzed Alkyne Hydration and Enzymatic Reduction. <i>ChemCatChem</i>, <i>10</i>(5), 920–924. https://doi.org/10.1002/cctc.201701752</div>
</div>
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dc.identifier.issn
1867-3880
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dc.identifier.uri
http://hdl.handle.net/20.500.12708/145879
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dc.description.abstract
Chemoenzymatic one-pot processes based on the combination of metal catalysis and biocatalysis open up highly attractive perspectives regarding the production of enantiopure compounds. By combining a gold-catalyzed hydration reaction with an enzymatic reduction, we present a straightforward and atom-economical chemoenzymatic method for the synthesis of secondary alcohols with excellent optical purity. Efficient cofactor recycling exploits the solvent of the metal-catalyzed step as an auxiliary substrate for the enzymatic step.
en
dc.language.iso
en
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dc.publisher
Wiley
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dc.relation.ispartof
ChemCatChem
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dc.subject
Inorganic Chemistry
en
dc.subject
Catalysis
en
dc.subject
Physical and Theoretical Chemistry
en
dc.subject
Organic Chemistry
en
dc.title
Easy Access to Enantiopure (S)- and (R)-Aryl Alkyl Alcohols by a Combination of Gold(III)-Catalyzed Alkyne Hydration and Enzymatic Reduction
en
dc.type
Artikel
de
dc.type
Article
en
dc.description.startpage
920
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dc.description.endpage
924
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dc.type.category
Original Research Article
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tuw.container.volume
10
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tuw.container.issue
5
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tuw.journal.peerreviewed
true
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tuw.peerreviewed
true
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tuw.researchTopic.id
X1
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tuw.researchTopic.name
außerhalb der gesamtuniversitären Forschungsschwerpunkte