<div class="csl-bib-body">
<div class="csl-entry">Stanetty, C. (2022, September 3). <i>Sweet tales from an aldehyde’s perspective</i> [Conference Presentation]. Young Investigator Workshop 2021/2022, Lissabon, Portugal.</div>
</div>
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dc.identifier.uri
http://hdl.handle.net/20.500.12708/154154
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dc.description
Eingeladener Vortrag
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dc.description.abstract
Carbohydrates are a fascinating part of Nature’s chiral pool and are provided in renewable fashion in great variety and abundance. It is a burden for extensive use by organic chemists, that only a small fraction of carbohydrates is readily available and consequently studied in great detail. Synthetic glyco-chemistry is challenging due to the structural density of both functional groups and stereochemistry. Adding to this complexity, an equilibrium exists between cyclic hemiacetals and the open chain carbonyl form (minor).
Graphical Abstract
It is this neglected molecular minority, with its intrinsically reactive aldehyde moiety, which is in the focus of our research. An operationally simple UV-based assay was developed to efficiently capture this relevant pre-equilibrium.1 This tool was utilized in the studied elongation of the carbohydrates via indium mediated acyloxyallylation (Fig. bottom)2 as well as the organocatalytic anomeric activation of reducing sugars by N-heterocyclic carbenes towards a controlled dehomologation method (Fig. top).3
en
dc.description.sponsorship
Fonds zur Förderung der wissenschaftlichen Forschung (FWF)
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dc.description.sponsorship
Fonds zur Förderung der wissenschaftlichen Forschung (FWF)
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dc.language.iso
en
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dc.subject
Carbohydrates
en
dc.subject
Kohlenhydrate
de
dc.title
Sweet tales from an aldehyde's perspective
en
dc.type
Presentation
en
dc.type
Vortrag
de
dc.relation.grantno
P 29138-N34
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dc.relation.grantno
J03449
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dc.type.category
Conference Presentation
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tuw.publication.invited
invited
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tuw.project.title
Kontrollierter Zuckerabbau durch N-Heterocyclische Carbene
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tuw.project.title
Flusschemie basierte Synthesestrategien zu LPS-Substrukturen
