<div class="csl-bib-body">
<div class="csl-entry">Stadler, G. (2021). <i>Synthesis and characterization of 17-epistanozolol- N-glucuronides for anti-doping purposes</i> [Diploma Thesis, Technische Universität Wien]. reposiTUm. https://doi.org/10.34726/hss.2021.86891</div>
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dc.identifier.uri
https://doi.org/10.34726/hss.2021.86891
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dc.identifier.uri
http://hdl.handle.net/20.500.12708/16687
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dc.description
Abweichender Titel nach Übersetzung der Verfasserin/des Verfassers
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dc.description.abstract
The aim of this thesis was the synthesis of urinary metabolites of the anabolic androgenic steroid stanozolol for anti-doping purposes and comparison with human metabolic molecules. Focus was put on the synthesis of the in position 17 epimerized metabolite of stanozolol and the N glucuronides of this molecule. Synthesis of 17-epistanozolol was carried out starting from stanozolol via sulfation of the tertiary alcohol and hydrolysis under basic conditions. N Glucuronides of this product were synthesized through modified Koenigs-Knorr glycosylation conditions with mercury salts for activation. The obtained synthetic metabolites were deprotected under basic conditions, fully characterized and compared with human urinary metabolic products.
en
dc.language
English
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dc.language.iso
en
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dc.rights.uri
http://rightsstatements.org/vocab/InC/1.0/
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dc.subject
Stanozolol
de
dc.subject
steroids
de
dc.subject
Stanozolol
en
dc.subject
Steroids
en
dc.title
Synthesis and characterization of 17-epistanozolol- N-glucuronides for anti-doping purposes
en
dc.title.alternative
Synthesis and Characterization of 17-Epistanozolol- N-Glucuronides for Anti-Doping Purposes
