<div class="csl-bib-body">
<div class="csl-entry">Weisz, M. (2021). <i>Asymmetric aziridination of cyclic enones via counterion enhanced organocatalysis</i> [Diploma Thesis, Technische Universität Wien]. reposiTUm. https://doi.org/10.34726/hss.2021.88740</div>
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dc.identifier.uri
https://doi.org/10.34726/hss.2021.88740
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dc.identifier.uri
http://hdl.handle.net/20.500.12708/17054
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dc.description
Abweichender Titel nach Übersetzung der Verfasserin/des Verfassers
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dc.description.abstract
The focus of the present thesis is the asymmetric aziridination of cyclic enones via counterion enhanced organocatalysis. In this approach, the catalyst system consists of a chiral diamine, which can be obtained from an amino-acid precursor, and an achiral phosphoric acid, which combine to form the catalyst salt. In order to determine the best performing catalyst system and the optimal reaction conditions, several amines, phosphoric acids, bases and solvents were screened. After optimizing the parameters, the asymmetric aziridination was successfully applied to a range of 3- and 4-substituted cyclohexenone substrates, in a final step. With this new catalyst system, excellent enantioselectivities as well as good yields could be achieved for several substrates and consequently, the versatility of the concept of counterion enhanced organocatalysis could be demonstrated.
en
dc.language
English
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dc.language.iso
en
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dc.rights.uri
http://rightsstatements.org/vocab/InC/1.0/
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dc.subject
Asymetrische Synthese
de
dc.subject
Stereochemie
de
dc.subject
Organokatalyse
de
dc.subject
Grüne Chemie
de
dc.subject
Asymetric Synthesis
en
dc.subject
Stereochemistry
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dc.subject
Organocatalysis
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dc.subject
Green Chemistry
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dc.title
Asymmetric aziridination of cyclic enones via counterion enhanced organocatalysis
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dc.title.alternative
Asymmetrische Azirdinierung von Cyclohexanonen durch Gegenion-dirigierender Organokatalyse