<div class="csl-bib-body">
<div class="csl-entry">Wenger, C., Fellner, A., Bucek, F., Werginz, P., & Rattay, F. (2023, November 2). <i>Simulating auditory nerve fiber response following micro-electrode stimulation: Comparing efficiency of electrode placements in the scala tympani and scala vestibul</i> [Conference Presentation]. ÖGBMT Annual Meeting 2023, Wien, Austria. http://hdl.handle.net/20.500.12708/190800</div>
</div>
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dc.identifier.uri
http://hdl.handle.net/20.500.12708/190800
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dc.description.abstract
The cochlear implant was the first effective and isstill the most common neuroprosthetic device which isemployed for people with severe to profound hearing loss. Torestore auditory perception, an array of micro-electrodes thatdeliver electrical pulses to the auditory nerve is surgicallyimplanted into the lower cochlea duct, the scala tympani(ST). However, implantation into the upper cavity, the scalavestibuli (SV) has been tested due to severe anatomicalobstruction or ossification of the ST. Clinical results revealedsimilar performance and thresholds for SV and ST cochlearimplant users. We present a simulation study of auditorynerve fibre response to monophasic stimulation of bothpolarities. Excitation profiles are compared for micro-electrodes placed in the SV and equivalent positions in theST. In total, 7 different electrode positions for 4 differentfibres have been investigated in a homogenous 2D model.Results for the intact fibres predict generally higher anodicthresholds in comparison to cathodic stimulation at the sameelectrode position and mostly lower thresholds for the SVelectrodes in comparison to their ST counterparts. In contrast,anodic thresholds are mostly lower than cathodic thresholdsfor the degenerated fibres. Furthermore, due to the increasedelectrode-fibre distance for degenerate fibres which havecompletely lost the dendrite, SV stimulation is lessbeneficial. However, for basal fibres and the clinicallyrelevant mid scala placement of the electrode the typicallyhigh thresholds remain similar for ST and SV positions
en
dc.language.iso
en
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dc.subject
auditory nerve fibres
en
dc.subject
extracellular stimulation
en
dc.subject
excitation patterns
en
dc.subject
cochlear implants
en
dc.subject
scala vestibuli
en
dc.title
Simulating auditory nerve fiber response following micro-electrode stimulation: Comparing efficiency of electrode placements in the scala tympani and scala vestibul
en
dc.type
Presentation
en
dc.type
Vortrag
de
dc.type.category
Conference Presentation
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tuw.researchTopic.id
C6
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tuw.researchTopic.name
Modeling and Simulation
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tuw.researchTopic.value
100
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tuw.publication.orgunit
E101-03 - Forschungsbereich Scientific Computing and Modelling
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tuw.author.orcid
0000-0002-3441-3167
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tuw.event.name
ÖGBMT Annual Meeting 2023
en
tuw.event.startdate
02-11-2023
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tuw.event.enddate
03-11-2023
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tuw.event.online
On Site
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tuw.event.type
Event for scientific audience
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tuw.event.place
Wien
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tuw.event.country
AT
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tuw.event.institution
Österreichische Gesellschaft für Biomedizinische Technik
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tuw.event.presenter
Wenger, Cornelia
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dc.relation.ispreviousversionof
10.1515/cdbme-2023-1202
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wb.sciencebranch
Mathematik
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wb.sciencebranch.oefos
1010
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wb.sciencebranch.value
100
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item.grantfulltext
none
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item.openairetype
conference paper not in proceedings
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item.fulltext
no Fulltext
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item.languageiso639-1
en
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item.openairecristype
http://purl.org/coar/resource_type/c_18cp
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item.cerifentitytype
Publications
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crisitem.author.dept
E101-03 - Forschungsbereich Scientific Computing and Modelling
-
crisitem.author.dept
E101-03 - Forschungsbereich Scientific Computing and Modelling
-
crisitem.author.dept
E363 - Institut für Biomedizinische Elektronik
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crisitem.author.dept
E101-03 - Forschungsbereich Scientific Computing and Modelling
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crisitem.author.orcid
0000-0002-3441-3167
-
crisitem.author.parentorg
E101 - Institut für Analysis und Scientific Computing
-
crisitem.author.parentorg
E101 - Institut für Analysis und Scientific Computing
-
crisitem.author.parentorg
E350 - Fakultät für Elektrotechnik und Informationstechnik
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crisitem.author.parentorg
E101 - Institut für Analysis und Scientific Computing
