<div class="csl-bib-body">
<div class="csl-entry">Scheibelreiter, V., Kalaus, H., & Stanetty, C. (2023, July 11). <i>Utilizing Fluorine-labelled 2-Aminobenzamidoximes to Distinguish Aldoses via 19F-NMR</i> [Poster Presentation]. 21st European Carbohydrate Symposium (Eurocarb21) 2023, Paris, France. https://doi.org/10.34726/5314</div>
</div>
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dc.identifier.uri
http://hdl.handle.net/20.500.12708/190876
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dc.identifier.uri
https://doi.org/10.34726/5314
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dc.description.abstract
Aldoses are structurally composed of a reactive aldehyde group and multiple hydroxy groups. Each specific sugar exhibits a defined stereochemistry of these alcoholic moieties. Being constitutional isomers, the differentiation between sugars, especially in mixtures, is challenging. Previously, we have described a photometric kinetic assay to determine the open-chain content of aldoses utilizing the selective reaction with 2-aminobenzamidoxime (ABAO). Herein, we have taken further advantage of this aldehyde-selective reaction, using it for a qualitative aldose assay based on 19F-NMR, a highly sensitive and fast method. The influence of the position of the F-label on the adduct formation rates was determined and derivatives of selected aldoses were prepared and the deviation of chemical shifts in 19F-NMR of the products were compared. While all four tested F-ABAO derivatives showed differences in shifts between the tested aldoses, one derivative was especially promising for the application in a qualitative sugar assay and the scope was expanded to a larger set of aldoses for this derivative.
en
dc.description.sponsorship
FWF - Österr. Wissenschaftsfonds
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dc.language.iso
en
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dc.rights.uri
http://creativecommons.org/licenses/by/4.0/
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dc.subject
Carbohydrate analysis
en
dc.subject
19F-NMR
en
dc.title
Utilizing Fluorine-labelled 2-Aminobenzamidoximes to Distinguish Aldoses via 19F-NMR
en
dc.type
Presentation
en
dc.type
Vortrag
de
dc.rights.license
Creative Commons Namensnennung 4.0 International
de
dc.rights.license
Creative Commons Attribution 4.0 International
en
dc.identifier.doi
10.34726/5314
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dc.relation.grantno
P 29138-N34
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dc.type.category
Poster Presentation
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tuw.project.title
Kontrollierter Zuckerabbau durch N-Heterocyclische Carbene
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tuw.researchinfrastructure
Zentrum für Kernspinresonanzspektroskopie
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tuw.researchTopic.id
X1
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tuw.researchTopic.name
Beyond TUW-research foci
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tuw.researchTopic.value
100
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tuw.publication.orgunit
E163 - Institut für Angewandte Synthesechemie
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tuw.author.orcid
0000-0001-8626-6165
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tuw.author.orcid
0000-0001-7692-6932
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dc.rights.identifier
CC BY 4.0
de
dc.rights.identifier
CC BY 4.0
en
tuw.event.name
21st European Carbohydrate Symposium (Eurocarb21) 2023
