<div class="csl-bib-body">
<div class="csl-entry">Schweifer, A., Malová Križková, P., Mereiter, K., & Hammerschmidt, F. (2017). Preparation of Nonradioactive Standards and a Precursor for a Hypoxia <sup>1</sup><sup>8</sup>F PET Tracer Derived from 1-(β-d-Galactopyranosyl)-2-nitroimidazole. <i>Synthesis: Journal of Synthetic Organic Chemistry</i>, <i>49</i>(13), 2933–2938. https://doi.org/10.1055/s-0036-1588991</div>
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dc.identifier.issn
0039-7881
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dc.identifier.uri
http://hdl.handle.net/20.500.12708/190893
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dc.description.abstract
Acetyl-protected 1-(β- d -galactopyranosyl)-2-nitroimidazole was converted to a potential precursor for a fluorine-18 labeled hypoxia tumor marker. Two nonradioactive standards, the 6′-deoxy-6′-fluorogalactosyl and the 4′-deoxy-4′-fluoroglucosyl analogue were also prepared. These 2-nitroimidazole nucleosides were prepared by a modified Vorbrüggen coupling.
en
dc.language.iso
en
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dc.publisher
GEORG THIEME VERLAG KG
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dc.relation.ispartof
Synthesis: Journal of Synthetic Organic Chemistry
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dc.subject
2-nitroimidazole
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dc.subject
d-galactose
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dc.subject
d-glucose
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dc.subject
nucleosides
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dc.subject
precursor
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dc.subject
tumor hypoxia
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dc.subject
[ F]fluoride 18
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dc.title
Preparation of Nonradioactive Standards and a Precursor for a Hypoxia ¹⁸F PET Tracer Derived from 1-(β-d-Galactopyranosyl)-2-nitroimidazole
