<div class="csl-bib-body">
<div class="csl-entry">Schuster, M. R., Dirkes, N., Key, F., Elgeti, S., & Behr, M. (2023). <i>Exploring the Influence of Parametrized Pulsatility on Left Ventricular Washout under LVAD Support: A Computational Study Using Reduced-Order Models</i>. arXiv. https://doi.org/10.48550/arXiv.2310.07443</div>
</div>
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dc.identifier.uri
http://hdl.handle.net/20.500.12708/190947
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dc.description.abstract
Medical therapy for patients with severe heart disease often relies on left ventricular assist devices (LVADs). It is an ongoing topic of research how complications like stagnation and thrombosis can be prevented by using artificial pulsatility. We study a parametric pulse profile and its effect on the left ventricular washout using a computational flow model. Based on finite element simulations, we construct reduced-order models to reduce the computational costs for evaluating the parametrized problem. We observe that a pulsatile flow rate improves the washout compared to a constant flow rate. In particular, we find that short, intense pulses wash out the left ventricle best, whereas the time between subsequent pulses plays no significant role.
en
dc.language.iso
en
-
dc.subject
left ventricular assist device
en
dc.subject
washout
en
dc.subject
finite element method
en
dc.subject
reduced-order modeling
en
dc.subject
gaussian process regression
en
dc.title
Exploring the Influence of Parametrized Pulsatility on Left Ventricular Washout under LVAD Support: A Computational Study Using Reduced-Order Models
en
dc.type
Preprint
en
dc.type
Preprint
de
dc.identifier.arxiv
2310.07443
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dc.contributor.affiliation
RWTH Aachen University, Germany
-
dc.contributor.affiliation
RWTH Aachen University, Germany
-
dc.contributor.affiliation
RWTH Aachen University, Germany
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tuw.researchTopic.id
C2
-
tuw.researchTopic.id
C4
-
tuw.researchTopic.id
C6
-
tuw.researchTopic.name
Computational Fluid Dynamics
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tuw.researchTopic.name
Mathematical and Algorithmic Foundations
-
tuw.researchTopic.name
Modeling and Simulation
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tuw.researchTopic.value
50
-
tuw.researchTopic.value
20
-
tuw.researchTopic.value
30
-
tuw.publication.orgunit
E317-01-1 - Forschungsgruppe Numerische Analyse- und Designmethoden
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tuw.publisher.doi
10.48550/arXiv.2310.07443
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tuw.author.orcid
0009-0001-5979-6627
-
tuw.author.orcid
0009-0009-2018-7304
-
tuw.author.orcid
0000-0001-6622-4806
-
tuw.author.orcid
0000-0002-4474-1666
-
tuw.author.orcid
0000-0003-4257-8276
-
tuw.publisher.server
arXiv
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wb.sciencebranch
Medizintechnik
-
wb.sciencebranch
Maschinenbau
-
wb.sciencebranch
Sonstige Technische Wissenschaften
-
wb.sciencebranch.oefos
2060
-
wb.sciencebranch.oefos
2030
-
wb.sciencebranch.oefos
2119
-
wb.sciencebranch.value
20
-
wb.sciencebranch.value
40
-
wb.sciencebranch.value
40
-
item.languageiso639-1
en
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item.fulltext
no Fulltext
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item.openairecristype
http://purl.org/coar/resource_type/c_816b
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item.grantfulltext
none
-
item.cerifentitytype
Publications
-
item.openairetype
preprint
-
crisitem.author.dept
RWTH Aachen University, Germany
-
crisitem.author.dept
RWTH Aachen University, Germany
-
crisitem.author.dept
E317-01-1 - Forschungsgruppe Numerische Analyse- und Designmethoden
-
crisitem.author.dept
E317-01 - Forschungsbereich Leichtbau
-
crisitem.author.dept
RWTH Aachen University, Germany
-
crisitem.author.orcid
0009-0001-5979-6627
-
crisitem.author.orcid
0009-0009-2018-7304
-
crisitem.author.orcid
0000-0001-6622-4806
-
crisitem.author.orcid
0000-0002-4474-1666
-
crisitem.author.orcid
0000-0003-4257-8276
-
crisitem.author.parentorg
E317-01 - Forschungsbereich Leichtbau
-
crisitem.author.parentorg
E317 - Institut für Leichtbau und Struktur-Biomechanik