<div class="csl-bib-body">
<div class="csl-entry">Templ, J., & Schnürch, M. (2023, July 11). <i>Mashing up Tsuji-Trost Reaction - A mechanochemical approach</i> [Poster Presentation]. 22nd European Symposium on Organic Chemistry 2023, Ghent, Belgium.</div>
</div>
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dc.identifier.uri
http://hdl.handle.net/20.500.12708/191878
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dc.description.abstract
A mechanochemical, solvent-free protocol for Tsuji–Trost allylation of O-, N-, and C-Nucleophiles using nontoxic, solid allyl trimethylammonium chloride as alternative allylating agent is presented. This method features fast reaction kinetics, very low catalyst loadings, high yields, mild conditions, and high functional group tolerance. Its potential for late-stage modifications of bioactive compounds is demonstrated through multiple examples.
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dc.description.sponsorship
FWF - Österr. Wissenschaftsfonds
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dc.language.iso
en
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dc.subject
Mechanochemistry
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dc.subject
Solvent-free
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dc.subject
Ammonium Salts
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dc.subject
Allylation
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dc.subject
Tsuji-Trost reaction
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dc.subject
Ball milling
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dc.title
Mashing up Tsuji-Trost Reaction - A mechanochemical approach
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dc.type
Presentation
en
dc.type
Vortrag
de
dc.relation.grantno
P 33064-N
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dc.type.category
Poster Presentation
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tuw.project.title
Substitution von gasförmigen Reagenzien durch Feststoffe