<div class="csl-bib-body">
<div class="csl-entry">Schneckenleitner, N., Mach, R., Mach-Aigner, A., & Zimmermann, C. (2023, September 22). <i>Contribution of DHN melanin to survival and growth of Neoarthrinium moseri in extreme environments</i> [Conference Presentation]. IUBMB Focused Meeting on Extremophilic Fungi (FUN-EX 2023), Ljubljana, Slovenia.</div>
</div>
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dc.identifier.uri
http://hdl.handle.net/20.500.12708/195046
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dc.description.abstract
Epiphyte Neoarthrinium moseri is a sordariomycete found in tropical forests in Colombia and Brunei.
Whole genome analysis revealed a high potential for secondary metabolite (SM) production and cultivation on different media resulted in the expression of different yet unknown SMs. Additionally, microbiological assessment using different types of stresses (salinity, pH, temperature) indicated tolerance of the fungus to extreme environments.
Under certain laboratory conditions, N. moseri forms black and tear-shaped conidia. The fungus shares this feature with its close relative Pestalotiopsis fici. We were able to identify the Biosynthetic Gene Cluster (BGC) responsible for the expression of 1,8-dyhydroxynaphthalene (DHN) melanin in N. moseri by comparing genomic data of
N. moseri and P. fici. Deletion of the according polyketide synthase (PKS) resulted in loss of black color and tear-like shape of the conidia. However, in both strains DHN melanin-deficiency is not lethal to the strain.
In this work we investigated the contribution of DHN melanin to the tolerance of
N. moseri to extreme environments. In addition to the already used test conditions for microbiological assessment (salinity, pH, temperature), we tested the wildtype and the DHN-melanin deficient strain for their susceptibility to among others oxidative and heavy metal stress.
en
dc.language.iso
en
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dc.subject
Neoarthrinium moseri
en
dc.subject
stress
en
dc.subject
melanin
en
dc.subject
secondary metabolism
en
dc.title
Contribution of DHN melanin to survival and growth of Neoarthrinium moseri in extreme environments
en
dc.type
Presentation
en
dc.type
Vortrag
de
dc.type.category
Conference Presentation
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tuw.researchTopic.id
X1
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tuw.researchTopic.name
Beyond TUW-research foci
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tuw.researchTopic.value
100
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tuw.publication.orgunit
E166-05-1 - Forschungsgruppe Synthetische Biologie und Molekulare Biotechnologie
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tuw.author.orcid
0000-0001-8663-0705
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tuw.author.orcid
0000-0003-2375-7244
-
tuw.author.orcid
0000-0002-7575-2317
-
tuw.author.orcid
0000-0002-6440-2100
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tuw.event.name
IUBMB Focused Meeting on Extremophilic Fungi (FUN-EX 2023)
en
tuw.event.startdate
19-09-2023
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tuw.event.enddate
22-09-2023
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tuw.event.online
On Site
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tuw.event.type
Event for scientific audience
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tuw.event.place
Ljubljana
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tuw.event.country
SI
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tuw.event.presenter
Schneckenleitner, Nadine
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wb.sciencebranch
Biologie
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wb.sciencebranch.oefos
1060
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wb.sciencebranch.value
100
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item.languageiso639-1
en
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item.openairetype
conference paper not in proceedings
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item.grantfulltext
none
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item.fulltext
no Fulltext
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item.cerifentitytype
Publications
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item.openairecristype
http://purl.org/coar/resource_type/c_18cp
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crisitem.author.dept
E166-05-3 - Forschungsgruppe Umweltmikrobiologie and Molekulare Diagnostik
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crisitem.author.dept
E166 - Institut für Verfahrenstechnik, Umwelttechnik und technische Biowissenschaften
-
crisitem.author.dept
E166-05 - Forschungsbereich Biochemische Technologie
-
crisitem.author.dept
E166-05-1 - Forschungsgruppe Synthetische Biologie und Molekulare Biotechnologie
-
crisitem.author.orcid
0000-0001-8663-0705
-
crisitem.author.orcid
0000-0003-2375-7244
-
crisitem.author.orcid
0000-0002-7575-2317
-
crisitem.author.orcid
0000-0002-6440-2100
-
crisitem.author.parentorg
E166-05 - Forschungsbereich Biochemische Technologie
-
crisitem.author.parentorg
E150 - Fakultät für Technische Chemie
-
crisitem.author.parentorg
E166 - Institut für Verfahrenstechnik, Umwelttechnik und technische Biowissenschaften
-
crisitem.author.parentorg
E166-05 - Forschungsbereich Biochemische Technologie
