<div class="csl-bib-body">
<div class="csl-entry">Barutel, C. M. A. (2024, February 5). <i>A generic theory for filament interaction in the cytoskeleton</i> [Poster Presentation]. Workshop Active Polymers and Filaments - Organization and Dynamics, Leiden, Netherlands (the).</div>
</div>
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dc.identifier.uri
http://hdl.handle.net/20.500.12708/197344
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dc.description.abstract
Living things keep themselves out of equilibrium by consuming energy from their surroundings in the form of nutrients or radiation. This allows them to move. On cellular scales, motion is driven by a dynamic network of polymer filaments (actin, microtubules) and crosslinking proteins, many of which act as molecular scale motors. Collectively this system of filaments, passive crosslinks and motors, is called the cytoskeleton. The large scale properties of this living material are shaped by the specifics of molecular scale interactions between cytoskeletal filaments. We seek to understand the forces and torques that filaments exchange. For this we need to understand the collective dynamics of crosslinking proteins that link cytoskeletal filaments. We tackle this problem by developing a theory that uses the fundamental physical principles of mass, number and momentum conservation and the symmetries of the system to derive generic equations of motion for crosslinks coupling two cytoskeltal f ilaments. In this way we can fully characterize crosslink effects between filaments, in a theory that is agnostic to microscale details.
en
dc.language.iso
en
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dc.subject
Biophysik
de
dc.title
A generic theory for filament interaction in the cytoskeleton
en
dc.type
Presentation
en
dc.type
Vortrag
de
dc.type.category
Poster Presentation
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tuw.researchTopic.id
M6
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tuw.researchTopic.name
Biological and Bioactive Materials
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tuw.researchTopic.value
100
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tuw.publication.orgunit
E134-04 - Forschungsbereich Biophysics
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tuw.event.name
Workshop Active Polymers and Filaments - Organization and Dynamics
