<div class="csl-bib-body">
<div class="csl-entry">Lebedeva, A., Handelshauser, M., Andriotis, O., Hager, B., Trattnig, S., Hirtler, L., Schreiner, M. M., Marchetti-Deschmann, M., & Thurner, P. J. (2024, July 1). <i>COMBINED AFM MICRO-INDENTATION AND MALDI MSI FOR CORRELATION OF MECHANICS AND COMPOSITION OF MENISCI</i> [Conference Presentation]. 29th Congress of the European Society of Biomechanics, Edinburgh, United Kingdom of Great Britain and Northern Ireland (the). http://hdl.handle.net/20.500.12708/209846</div>
</div>
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dc.identifier.uri
http://hdl.handle.net/20.500.12708/209846
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dc.description.abstract
Introduction
Meniscus degeneration leads to changes in load
distribution and loss of cartilage volume, which may
cause chronic pain and lead to knee osteoarthritis. For
better clinical treatment the physico-chemical hallmarks
of meniscus degeneration need further elucidation. In
this study, we present a proof of principle for multi-
modal physico-chemical assessment. Mechanical
properties and chemical composition of the same
meniscal tissue sections were assessed via atomic-force
microscopy (AFM) micro-indentation and matrix-
assisted laser desorption ionization (MALDI) mass
spectrometric imaging (MSI), respectively. We
hypothesized a correlation between indentation modulus
and proteomic composition.
en
dc.language.iso
en
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dc.subject
Tissue Biomechanics
en
dc.title
COMBINED AFM MICRO-INDENTATION AND MALDI MSI FOR CORRELATION OF MECHANICS AND COMPOSITION OF MENISCI
en
dc.type
Presentation
en
dc.type
Vortrag
de
dc.contributor.affiliation
Medical University of Vienna, Austria
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dc.contributor.affiliation
Medical University of Vienna, Austria
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dc.contributor.affiliation
Medical University of Vienna, Austria
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dc.contributor.affiliation
Medical University of Vienna, Austria
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dc.type.category
Conference Presentation
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tuw.researchTopic.id
M6
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tuw.researchTopic.name
Biological and Bioactive Materials
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tuw.researchTopic.value
100
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tuw.publication.orgunit
E317-02 - Forschungsbereich Biomechanik
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tuw.publication.orgunit
E164-01-1 - Forschungsgruppe Massenspektrometrische Bio- und Polymeranalytik
