<div class="csl-bib-body">
<div class="csl-entry">Zoratto, S., Kremslehner, C., Schirato, M., Gendronneau, G., Tessier, A., Gruber, F., & Marchetti-Deschmann, M. (2025, September 29). <i>Mapping Spatial Lipid Distribution Across Skin Layers and Associated Pathways in Human Skin and Skin Equivalents by MALDI FTICR MSI</i> [Conference Presentation]. International Mass Spectrometry Imaging Society Conference III (3rd IMSIS 2025), Davis, United States of America (the).</div>
</div>
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dc.identifier.uri
http://hdl.handle.net/20.500.12708/223479
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dc.description.abstract
This study investigates lipid distributions in human skin biopsies and in vitro skin equivalents (SE) using high-resolution MALDI FTICR MSI combined with HPLC-MS/MS. SE and native skin share key spatial lipid features, particularly in the stratum corneum and epidermis. Pathway analysis further supports the biological relevance of detected lipids. These findings support the use of SE as a reproducible model for spatial lipidomics under defined conditions.
en
dc.language.iso
en
-
dc.subject
MALDI FTICR MSI
en
dc.subject
lipidomics
en
dc.subject
skin aging
en
dc.subject
human biopsies
en
dc.subject
fibroblast cultures
en
dc.subject
spatial analysis
en
dc.subject
cellular senescence
en
dc.title
Mapping Spatial Lipid Distribution Across Skin Layers and Associated Pathways in Human Skin and Skin Equivalents by MALDI FTICR MSI
en
dc.type
Presentation
en
dc.type
Vortrag
de
dc.contributor.affiliation
Medical University of Vienna, Austria
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dc.contributor.affiliation
Christian Doppler Laboratory for Thermoelectricity, Austria
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dc.contributor.affiliation
Medical University of Vienna, Austria
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dc.type.category
Conference Presentation
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tuw.researchTopic.id
M6
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tuw.researchTopic.name
Biological and Bioactive Materials
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tuw.researchTopic.value
100
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tuw.publication.orgunit
E164-01-1 - Forschungsgruppe Massenspektrometrische Bio- und Polymeranalytik
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tuw.publication.orgunit
E056-04 - Fachbereich TU-DX: Towards Applications of 2D Materials
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tuw.publication.orgunit
E056-12 - Fachbereich ENROL DP
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tuw.publication.orgunit
E056-14 - Fachbereich Mature Tissue
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tuw.author.orcid
0000-0002-1491-3404
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tuw.author.orcid
0000-0002-3281-9841
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tuw.author.orcid
0000-0002-8060-7851
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tuw.event.name
International Mass Spectrometry Imaging Society Conference III (3rd IMSIS 2025)
en
tuw.event.startdate
29-09-2025
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tuw.event.enddate
02-10-2025
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tuw.event.online
On Site
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tuw.event.type
Event for scientific audience
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tuw.event.place
Davis
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tuw.event.country
US
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tuw.event.presenter
Zoratto, Samuele
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tuw.event.track
Single Track
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wb.sciencebranch
Chemie
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wb.sciencebranch.oefos
1040
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wb.sciencebranch.value
100
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item.openairetype
conference paper not in proceedings
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item.openairecristype
http://purl.org/coar/resource_type/c_18cp
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item.cerifentitytype
Publications
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item.languageiso639-1
en
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item.grantfulltext
none
-
item.fulltext
no Fulltext
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crisitem.author.dept
E164-01-1 - Forschungsgruppe Massenspektrometrische Bio- und Polymeranalytik
-
crisitem.author.dept
Medical University of Vienna, Austria
-
crisitem.author.dept
Christian Doppler Laboratory for Thermoelectricity, Austria
-
crisitem.author.dept
Medical University of Vienna, Austria
-
crisitem.author.dept
E164-01-1 - Forschungsgruppe Massenspektrometrische Bio- und Polymeranalytik
-
crisitem.author.orcid
0000-0002-1491-3404
-
crisitem.author.orcid
0000-0002-8060-7851
-
crisitem.author.parentorg
E164-01 - Forschungsbereich Imaging und Instrumentelle Analytische Chemie
-
crisitem.author.parentorg
E164-01 - Forschungsbereich Imaging und Instrumentelle Analytische Chemie
