<div class="csl-bib-body">
<div class="csl-entry">Mikoczi, D., Scharinger, F., Bin, D. D., & Schröder, K. (2025, September 17). <i>Shining new light on the synthesis of lactams: photochemical synthesis of oxindole derivatives</i> [Poster Presentation]. Photoexciting Molecules 2025, Klosterneuburg, Austria.</div>
</div>
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dc.identifier.uri
http://hdl.handle.net/20.500.12708/223950
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dc.description.abstract
Oxindoles are important scaffolds in medicinal chemistry, found in many natural products and drugs. We present a new visible-light-driven method for synthesizing oxindoles via intramolecular radical cyclization. This mild and sustainable approach uses decarboxylation of carboxylic acids to generate carbamoyl radicals that enable ring closure. The reaction shows broad functional group tolerance, allowing diverse modifications on both the olefin and amine component. This method enhances structural diversification of oxindoles and expands photochemistry’s role in heterocycle synthesis for drug discovery.
en
dc.language.iso
en
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dc.subject
Photoredox catalysis
en
dc.subject
Indole derivatives
en
dc.subject
radical cyclization
en
dc.title
Shining new light on the synthesis of lactams: photochemical synthesis of oxindole derivatives
en
dc.type
Presentation
en
dc.type
Vortrag
de
dc.contributor.affiliation
TU Wien, Austria
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dc.type.category
Poster Presentation
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tuw.researchTopic.id
M6
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tuw.researchTopic.id
M4
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tuw.researchTopic.name
Biological and Bioactive Materials
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tuw.researchTopic.name
Non-metallic Materials
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tuw.researchTopic.value
75
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tuw.researchTopic.value
25
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tuw.publication.orgunit
E163-03-5 - Forschungsgruppe Nachhaltige organische Synthese und Katalyse
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tuw.publication.orgunit
E056-09 - Fachbereich CO2 Refinery
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tuw.author.orcid
0000-0001-8690-3785
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tuw.author.orcid
0000-0002-2515-9873
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tuw.event.name
Photoexciting Molecules 2025
en
tuw.event.startdate
17-09-2025
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tuw.event.enddate
19-09-2025
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tuw.event.online
On Site
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tuw.event.type
Event for scientific audience
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tuw.event.place
Klosterneuburg
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tuw.event.country
AT
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tuw.event.institution
Institute of Science and Technology Austria
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tuw.event.presenter
Mikoczi, Dorottya
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tuw.event.track
Single Track
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wb.sciencebranch
Chemie
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wb.sciencebranch
Chemische Verfahrenstechnik
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wb.sciencebranch
Pharmazie, Pharmakologie, Toxikologie
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wb.sciencebranch.oefos
1040
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wb.sciencebranch.oefos
2040
-
wb.sciencebranch.oefos
3012
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wb.sciencebranch.value
60
-
wb.sciencebranch.value
20
-
wb.sciencebranch.value
20
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item.openairetype
conference poster not in proceedings
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item.openairecristype
http://purl.org/coar/resource_type/c_18co
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item.cerifentitytype
Publications
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item.languageiso639-1
en
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item.grantfulltext
none
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item.fulltext
no Fulltext
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crisitem.author.dept
E163-03-5 - Forschungsgruppe Nachhaltige organische Synthese und Katalyse
-
crisitem.author.dept
E163-03-5 - Forschungsgruppe Nachhaltige organische Synthese und Katalyse
-
crisitem.author.dept
TU Wien, Austria
-
crisitem.author.dept
E163-03-5 - Forschungsgruppe Nachhaltige organische Synthese und Katalyse
-
crisitem.author.orcid
0000-0001-8690-3785
-
crisitem.author.orcid
0000-0002-2515-9873
-
crisitem.author.parentorg
E163-03 - Forschungsbereich Organische und Biologische Chemie
-
crisitem.author.parentorg
E163-03 - Forschungsbereich Organische und Biologische Chemie
-
crisitem.author.parentorg
E163-03 - Forschungsbereich Organische und Biologische Chemie
