<div class="csl-bib-body">
<div class="csl-entry">Schnürch, M. (2025, May 22). <i>„The best solvent is no solvent – exploring the potential of mechanochemical organic synthesis”</i> [Presentation]. Internes Seminar TUM School of Natural Sciences 2025, München, Germany.</div>
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dc.identifier.uri
http://hdl.handle.net/20.500.12708/223995
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dc.description.abstract
In recent years, mechanochemistry has revived as an important method in modern synthetic chemistry.[1] Especially en route to more sustainable and environmentally benign chemical processes, mechanochemical transformations are privileged,[2] since this approach offers important advantages: the ability to conduct conventional synthetic reactions without the need for solvents coupled with rapid reaction kinetics. These unique features make mechanochemistry highly attractive for both industrial applications and fundamental research across diverse fields, including material science, inorganic chemistry, and organic chemistry.
Hence, we started a program to investigate the possibilities for carrying out fundamental organic transformations under solvent free conditions using a mechanochemical setup. Herein we report our results on mechanochemical Tsuji-Trost allylations,[3] Wittig reactions,[4] C(sp3)-H functionalization,[5] and Diels-Alder reactions as well as multistep sequences thereof.
1 J. L. Howard, Q. Cao, D. L. Browne, Chemical Science 2018, 9, 3080.
2 E. Colacino, F. Garcia, Mechanochemistry and Emerging Technologies for Sustainable Chemical Manufacturing, CRC Press, 2023, ISBN: 1000891623, 9781000891621
3 J. Templ, M. Schnürch, Angew. Chem. Int. Ed. 2024, 63, e202314637
4 J. Templ, M. Schnürch, Angew. Chem. Int. Ed. 2024, 63, e202411536.
5 N. K. Narayanan, M. Schnürch, ChemCatChem 2024, 0, e202401613
en
dc.description.sponsorship
Boehringer Ingelheim RCV GmbH & Co KG
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dc.description.sponsorship
FWF - Österr. Wissenschaftsfonds
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dc.description.sponsorship
European Commission
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dc.language.iso
en
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dc.subject
Organic Synthesis
en
dc.subject
Mechanochemical Synthesis
en
dc.subject
Mechanochemistry
en
dc.subject
Ball milling
en
dc.title
„The best solvent is no solvent – exploring the potential of mechanochemical organic synthesis”
en
dc.type
Presentation
en
dc.type
Vortrag
de
dc.relation.grantno
903817
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dc.relation.grantno
P 33064-N
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dc.relation.grantno
860762
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dc.type.category
Presentation
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tuw.publication.invited
invited
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tuw.project.title
Mechanochemische Synthese in der Medizinischen Chemie
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tuw.project.title
Substitution von gasförmigen Reagenzien durch Feststoffe
