<div class="csl-bib-body">
<div class="csl-entry">Schnürch, M., Templ, J., & Biedermann, N. (2025, June 5). <i>Organic Reaction Cascades via Mechanochemical Synthesis</i> [Conference Presentation]. Mech´cheM 2025 : New forces in Mechanochemistry, Montpellier, France. http://hdl.handle.net/20.500.12708/224018</div>
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dc.identifier.uri
http://hdl.handle.net/20.500.12708/224018
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dc.description.abstract
In recent years, mechanochemical organic synthesis has gained more and more interest in the community and emerged from the role of a niche application to a more widely applied method. This is promoted by factors such as the aim to reduce waste in chemical synthesis, where solvents are the biggest contributor, and also due to increasing restrictions for the use of established organic solvents. Hence, establishing fundamental organic reactions under solvent free conditions is imperative.
Along this line, we report on a set of such transformations including Tsuji-Trost allylations, Wittig reactions, C(sp3)-H functionalization, and Diels-Alder reactions (unpublished). Furthermore, it will be demonstrated, that these transformations can be incorporated in multistep reaction sequences without isolation of intermediate products. Most importantly, it will be shown, that the methods are applicable to compounds of relevance as active pharmaceutical ingredients.
en
dc.description.sponsorship
FWF - Österr. Wissenschaftsfonds
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dc.description.sponsorship
European Commission
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dc.language.iso
en
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dc.subject
Cascade reactions
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dc.subject
mechanochemistry
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dc.subject
solvent free chemistry
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dc.title
Organic Reaction Cascades via Mechanochemical Synthesis
en
dc.type
Presentation
en
dc.type
Vortrag
de
dc.relation.grantno
P 33064-N
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dc.relation.grantno
860762
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dc.type.category
Conference Presentation
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tuw.project.title
Substitution von gasförmigen Reagenzien durch Feststoffe
