<div class="csl-bib-body">
<div class="csl-entry">Ret, D., Garcia de Otazo Hernandez, D., Sabatino, G., Keppler, S., & Untersmayr, E. (2025, July 10). <i>Role of Sialic Acid and Glycosylations as Biomarkers for Severity Stratification in Post-Viral Infection Syndrome</i> [Conference Presentation]. The 22nd European Carbohydrate Symposium (EUROCARB22 2025), Gdansk, Poland. http://hdl.handle.net/20.500.12708/224458</div>
</div>
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dc.identifier.uri
http://hdl.handle.net/20.500.12708/224458
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dc.description.abstract
Our group focuses on the study of sialic acid and sialylated glycans in inflammatory diseases. In this work, we aim to find better biomarkers for severity stratification in post-viral syndrome using a glycomics approach. Glycomics is the communication language of organisms, based on a sugar code (glycans) imprinted on tissues, proteins, and lipids. Many diseases, such as autoimmune disorders and pathogenic infections, has an alterered sugar code in the organism, leading to inflammation.
N-glycome was characterized in serum and purified IgG by MALDI mass spectrometry in positive mode after purification and derivatization with methylamine. After labelling with DMBA, total sialic acid content was quantified by HPLC-RP-FL.
We observed variations in N-glycome and sialic acid concentration between patients and controls, suggesting the involvement of sialic acid in the severity of post-viral fatigue syndrome.
en
dc.description.sponsorship
WWTF Wiener Wissenschafts-, Forschu und Technologiefonds
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dc.language.iso
en
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dc.subject
sialic acid
en
dc.subject
post-viral syndrome
en
dc.subject
Glycomics
en
dc.title
Role of Sialic Acid and Glycosylations as Biomarkers for Severity Stratification in Post-Viral Infection Syndrome
en
dc.type
Presentation
en
dc.type
Vortrag
de
dc.contributor.affiliation
TU Wien, Austria
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dc.contributor.affiliation
Medical University of Graz, Austria
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dc.contributor.affiliation
Medical University of Vienna, Austria
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dc.relation.grantno
ME-CFS24-016
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dc.type.category
Conference Presentation
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tuw.project.title
Exploring the Glycome: Identifying Glycosylation-Related Biomarkers in Chronic Fatigue Syndrome
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tuw.researchTopic.id
M6
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tuw.researchTopic.name
Biological and Bioactive Materials
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tuw.researchTopic.value
100
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tuw.publication.orgunit
E163-02-1 - Forschungsgruppe Polymerchemie und Technologie
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tuw.author.orcid
0000-0002-7461-0923
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tuw.author.orcid
0000-0003-0126-3868
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tuw.author.orcid
0000-0002-9010-8044
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tuw.author.orcid
0000-0002-1963-499X
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tuw.event.name
The 22nd European Carbohydrate Symposium (EUROCARB22 2025)
en
tuw.event.startdate
06-07-2025
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tuw.event.enddate
10-07-2025
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tuw.event.online
On Site
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tuw.event.type
Event for scientific audience
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tuw.event.place
Gdansk
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tuw.event.country
PL
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tuw.event.institution
European Carbohydrate Organisation
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tuw.event.presenter
Ret, Davide
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tuw.event.track
Multi Track
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wb.sciencebranch
Chemie
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wb.sciencebranch
Chemische Verfahrenstechnik
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wb.sciencebranch
Pharmazie, Pharmakologie, Toxikologie
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wb.sciencebranch.oefos
1040
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wb.sciencebranch.oefos
2040
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wb.sciencebranch.oefos
3012
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wb.sciencebranch.value
60
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wb.sciencebranch.value
20
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wb.sciencebranch.value
20
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item.openairetype
conference paper not in proceedings
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item.openairecristype
http://purl.org/coar/resource_type/c_18cp
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item.cerifentitytype
Publications
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item.languageiso639-1
en
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item.grantfulltext
none
-
item.fulltext
no Fulltext
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crisitem.author.dept
E163-02-1 - Forschungsgruppe Polymerchemie und Technologie
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crisitem.author.dept
TU Wien, Austria
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crisitem.author.dept
E163-02-1 - Forschungsgruppe Polymerchemie und Technologie
