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<div class="csl-entry">Anschuber, M., Pollice, R., & Schnürch, M. (2019). Rhodium-catalyzed direct alkylation of benzylic amines using alkyl bromides. <i>Monatshefte Für Chemie - Chemical Monthly</i>. https://doi.org/10.1007/s00706-018-2305-9</div>
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Within this contribution, the development and substrate scope evaluation of a direct alkylation protocol of the C(sp3)–H bond of benzylic amines using alkyl bromides is reported. This pyridine-directed method is initiated by elimination of the alkyl bromide to a terminal olefin, which is then the true alkylating agent.
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dc.language
English
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dc.language.iso
en
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dc.publisher
Springer
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dc.relation.ispartof
Monatshefte für Chemie - Chemical Monthly
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dc.rights.uri
http://creativecommons.org/licenses/by/4.0/
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dc.subject
C–H activation
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dc.subject
C–H functionalization
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dc.subject
Directing group Catalysis
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dc.title
Rhodium-catalyzed direct alkylation of benzylic amines using alkyl bromides