<div class="csl-bib-body">
<div class="csl-entry">Alcaráz, M. R., Schwaighofer, A., Goicoechea, H., & Lendl, B. (2017). Application of MCR-ALS to reveal intermediate conformations in the thermally induced α-β transition of poly-l-lysine monitored by FT-IR spectroscopy. <i>Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy</i>, <i>185</i>, 304–309. https://doi.org/10.1016/j.saa.2017.05.005</div>
</div>
The final publication is available via <a href="https://doi.org/10.1016/j.saa.2017.05.005" target="_blank">https://doi.org/10.1016/j.saa.2017.05.005</a>.
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dc.description.abstract
Temperature-induced conformational transitions of poly-L-lysine were monitored with Fourier-transform infrared (FT-IR) spectroscopy between 10 °C and 70 °C. Chemometric analysis ofdynamic IR spectra was performed by multivariate curve analysis–alternating least squares (MCR-ALS) ofthe amide I′ and amide II′ spectral region. With this approach, the pure spectral and concentration profiles ofthe conformational transitionwere obtained. Beside the initial α-helical, the intermediate random coil/extended helices and the final β-sheet structure, an additional intermediate PLL conformation was identified and attributed to a transient β-sheet structure.
en
dc.description.sponsorship
Austrian research funding association (FFG)
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dc.language
English
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dc.language.iso
en
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dc.publisher
Elsevier B.V.
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dc.relation.ispartof
Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy
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dc.rights.uri
http://creativecommons.org/licenses/by-nc-nd/4.0/
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dc.subject
Fourier transform infrared spectroscopy
en
dc.subject
Multivariate curve analysis–alternating least squares
en
dc.subject
Secondary structure
en
dc.subject
Conformational analysis
en
dc.subject
Poly-L-lysine
en
dc.title
Application of MCR-ALS to reveal intermediate conformations in the thermally induced α-β transition of poly-l-lysine monitored by FT-IR spectroscopy
en
dc.type
Article
en
dc.type
Artikel
de
dc.rights.license
Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International
en
dc.rights.license
Creative Commons Namensnennung - Nicht kommerziell - Keine Bearbeitungen 4.0 International
de
dc.contributor.affiliation
National University of the Littoral, Argentina
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dc.description.startpage
304
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dc.description.endpage
309
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dc.relation.grantno
843546
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dc.rights.holder
Elsevier 2019
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dc.type.category
Original Research Article
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tuw.container.volume
185
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tuw.journal.peerreviewed
true
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tuw.peerreviewed
true
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tuw.version
am
-
wb.publication.intCoWork
International Co-publication
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dcterms.isPartOf.title
Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy
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tuw.publication.orgunit
E164 - Institut für Chemische Technologien und Analytik
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tuw.publisher.doi
10.1016/j.saa.2017.05.005
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dc.identifier.eissn
1873-3557
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dc.identifier.libraryid
AC15518675
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dc.identifier.urn
urn:nbn:at:at-ubtuw:3-7531
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tuw.author.orcid
0000-0003-2714-7056
-
tuw.author.orcid
0000-0003-3838-5842
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dc.rights.identifier
CC BY-NC-ND 4.0
en
dc.rights.identifier
CC BY-NC-ND 4.0
de
wb.sci
true
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item.languageiso639-1
en
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item.openairetype
research article
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open
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item.fulltext
with Fulltext
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item.cerifentitytype
Publications
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item.mimetype
application/pdf
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item.openairecristype
http://purl.org/coar/resource_type/c_2df8fbb1
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item.openaccessfulltext
Open Access
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crisitem.author.dept
E164 - Institut für Chemische Technologien und Analytik
-
crisitem.author.dept
E164-02-1 - Forschungsgruppe Prozessanalytik
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crisitem.author.dept
National University of the Littoral
-
crisitem.author.dept
E164-02 - Forschungsbereich Umwelt-, Prozessanalytik und Sensoren
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crisitem.author.orcid
0000-0003-2714-7056
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crisitem.author.orcid
0000-0003-3838-5842
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crisitem.author.parentorg
E150 - Fakultät für Technische Chemie
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crisitem.author.parentorg
E164-02 - Forschungsbereich Umwelt-, Prozessanalytik und Sensoren
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crisitem.author.parentorg
E164 - Institut für Chemische Technologien und Analytik
