<div class="csl-bib-body">
<div class="csl-entry">Managhebaty, M. A. (2017). <i>Microfluidic chip for rapid calcium determination in human milk</i> [Diploma Thesis, Technische Universität Wien]. reposiTUm. https://doi.org/10.34726/hss.2017.30128</div>
</div>
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dc.identifier.uri
https://doi.org/10.34726/hss.2017.30128
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dc.identifier.uri
http://hdl.handle.net/20.500.12708/9816
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dc.description.abstract
Current methods for determination of calcium content in human milk are based on standard laboratory experiments, which are time consuming and require specially trained personnel. Available instruments to accomplish these experiments are usually designed for a sample volume in the range of several milliliters. These approaches are not applicable for in-situ determination of calcium. In this thesis, an inexpensive and rapid technique for quantification of calcium in human milk is presented, using only 5 μL of sample fluid for operation and determining results within 2-3 minutes. Principles of colorimetric chemical analytical methods are miniaturized to fit a specific microfluidic chip, fabricated based on standard dry film photoresist technology. Downscaling challenges such as fluid flow and mixing, are brought under control after implementation of phaseguides in the chip design and utilizing hydrogel concept, respectively. Future steps can be taken toward developing a compact device to replace the spectrometric instruments, making it an ideal analytical device for non-laboratory environments. This method can also be generalized as a new comprehensive technique for colorimetric assays in micrometer scale for other chemical substances.
en
dc.language
English
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dc.language.iso
en
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dc.rights.uri
http://rightsstatements.org/vocab/InC/1.0/
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dc.subject
Microfluidics
en
dc.subject
calcium detection
en
dc.title
Microfluidic chip for rapid calcium determination in human milk
en
dc.type
Thesis
en
dc.type
Hochschulschrift
de
dc.rights.license
In Copyright
en
dc.rights.license
Urheberrechtsschutz
de
dc.identifier.doi
10.34726/hss.2017.30128
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dc.contributor.affiliation
TU Wien, Österreich
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dc.rights.holder
Mohammad Amin Managhebaty
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dc.publisher.place
Wien
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tuw.version
vor
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tuw.thesisinformation
Technische Universität Wien
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dc.contributor.assistant
Haller, Anna
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tuw.publication.orgunit
E366 - Institut für Sensor- und Aktuatorsysteme
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dc.type.qualificationlevel
Diploma
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dc.identifier.libraryid
AC13753184
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dc.description.numberOfPages
78
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dc.identifier.urn
urn:nbn:at:at-ubtuw:1-100927
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dc.thesistype
Diplomarbeit
de
dc.thesistype
Diploma Thesis
en
dc.rights.identifier
In Copyright
en
dc.rights.identifier
Urheberrechtsschutz
de
tuw.advisor.staffStatus
staff
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tuw.assistant.staffStatus
staff
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item.languageiso639-1
en
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item.mimetype
application/pdf
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item.openairecristype
http://purl.org/coar/resource_type/c_bdcc
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item.fulltext
with Fulltext
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item.openairetype
master thesis
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item.grantfulltext
open
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item.openaccessfulltext
Open Access
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item.cerifentitytype
Publications
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crisitem.author.dept
E366 - Institut für Sensor- und Aktuatorsysteme
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crisitem.author.parentorg
E350 - Fakultät für Elektrotechnik und Informationstechnik