Title: Data models, graph analysis, and information retrieval from biological data
Language: English
Authors: Fechete, Raul
Qualification level: Diploma
Keywords: Systembiologie; Omics; Biologische Daten; Graphen; Datenbanken; Kürzeste Pfade
systems biology; omics; biological data; graphs; databases; shortest paths
Advisor: Freund, Rudolf
Assisting Advisor: Mayer, Bernd
Issue Date: 2009
Number of Pages: 83
Qualification level: Diploma
Abstract: 
This thesis introduces a possible approach to information extraction from a biological context, by building a molecular dependency network.
Our aim is to optimize hypothesis generation for laboratory experiments, with the ultimate goal of disease-associated biomarker and drug target discovery.
We present a three-stage method involving data warehousing, scientific information consolidation and analysis. Further, we investigate the method by running tests using specific datasets from B-cell lymphoma and renal transplant ischemia reperfusion injury.
URI: https://resolver.obvsg.at/urn:nbn:at:at-ubtuw:1-25993
http://hdl.handle.net/20.500.12708/11187
Library ID: AC05040222
Organisation: E185 - Institut für Computersprachen 
Publication Type: Thesis
Hochschulschrift
Appears in Collections:Thesis

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