Magnesium (Mg) and its alloys possess ideal characteristics in mechanical properties and biological acceptance, and thus are of great promise for deployment as implant material, particularly in surgical stabilisation of bone fractures. The relatively fast degradation ability avoids second surgeries for removal of the implant. Essential for their applicability is a sufficient load baring capacity for a clinically relevant time frame, which is directly linked to a reliable degradation rate and good bone ingrowth. , The purpose of this study was therefore to (1) analyse the general applicability of Mg-based screws for their use in cortical bone (2) study whether an improved degradation and therefore biomechanical performance can be achieved by chemical surface treatment.