Record link: 
http://hdl.handle.net/20.500.12708/141731
-
Title: 
Investigation of a New Type I Baeyer-​Villiger Monooxygenase from Amycolatopsis thermoflava Revealed High Thermodynamic but Limited Kinetic Stability
en
Citation: 
Mansouri, H. R., Mihovilovic, M. D., & Rudroff, F. (2020). Investigation of a New Type I Baeyer-​Villiger Monooxygenase from Amycolatopsis thermoflava Revealed High Thermodynamic but Limited Kinetic Stability. ChemBioChem, 21(7), 971–977. https://doi.org/10.1002/cbic.201900501
-
Publisher DOI: 
10.1002/cbic.201900501
-
Publication Type: 
Article - Original Research Article
en
Language: 
English
-
Authors: 
Mansouri, Hamid R. 
Mihovilovic, Marko D. 
Rudroff, Florian 
-
Organisational Unit: 
E163-03-4 - Forschungsgruppe Bioorganische Synthesechemie 
-
Journal: 
ChemBioChem 
-
ISSN: 
1439-4227
-
Date (published): 
2020
-
Number of Pages: 
7
-
Publisher: 
WILEY-V C H VERLAG GMBH
-
Peer reviewed: 
Yes
-
Keywords: 
biocatalysis; Biochemistry; Molecular Biology; Organic Chemistry; Molecular Medicine; enzyme catalysis; enzyme stability; in silico analysis; monooxygenases
-
Abstract: 
In silico screening: A Baeyer-Villiger monooxygenase (BVMO) from a thermophilic origin is identified through an in silico approach. There is a strong deviation between the thermodynamic and kinetic stabilities of the new BVMO, which might have a major impact for future enzyme discovery of BVMOs and their synthetic applications.
en
Research Areas: 
Sustainable Production and Technologies: 100%
-
Science Branch: 
Chemie
Industrielle Biotechnologie
-
Appears in Collections:
Article

Show full item record

Items in reposiTUm are protected by copyright, with all rights reserved, unless otherwise indicated.

Google ScholarTM

Check