Korotkova, E. I., Freinbichler, W., Linert, W., Dorozhko, E. V., Bukkel, M. V., Plotnikov, E. V., & Voronova, O. A. (2013). Study of Total Antioxidant Activity of Human Serum Blood in the Pathology of Alcoholism. Molecules, 18(2), 1811–1818. https://doi.org/10.3390/molecules18021811
E163-01-2 - Forschungsgruppe Koordinationschemie und bio-anorganische Chemie
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Journal:
Molecules
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ISSN:
1420-3049
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Date (published):
30-Jan-2013
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Number of Pages:
8
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Publisher:
MDPI
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Peer reviewed:
Yes
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Keywords:
Pharmaceutical Science; Analytical Chemistry; Physical and Theoretical Chemistry; Drug Discovery; Organic Chemistry; Molecular Medicine; Chemistry (miscellaneous); voltammetry; total antioxidant activity; human serum blood; spectrophotometry
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Abstract:
The total antioxidant activity (TAA) of human serum blood of patients suffering from alcoholism was tested by cathode voltammetry with a model process of oxygen electroreduction. A known spectrophotometrical method was used for comparison. As results the total antioxidant activity of serum blood of patients with alcoholism was estimated by voltammetry during therapy in hospital. It was shown the TAA of serum blood of patients in pathology before and after treatment is lower than that one of healthy people. However, during the process of 10 days of alcoholism treatment the TAA coefficient increases. The relationship between the coefficient of total antioxidant activity of human serum blood and the stage of treatment was detected.