Ell, M. F., Zeitler, R., Thewes, R., & Zeck, G. (2023). Label-free Identification of Nonelectrogenic Cancer Cells using Adhesion Noise. In 2023 IEEE BioSensors Conference (BioSensors) (pp. 1–4). IEEE. https://doi.org/10.34726/5234
London, United Kingdom of Great Britain and Northern Ireland (the)
-
Number of Pages:
4
-
Publisher:
IEEE, Piscataway
-
Keywords:
CMOS-based microelectrode arrays; Cell adhesion noise; HT-29 cell; Microelectrodes; Power system measurements; Adhesives; Optical recording; Voltage; Array; Biosensors
en
Abstract:
Time-continuous detection of cells on substrates without the need of optical microscopic imaging is of broad interest in biotechnological applications. We present a method how to detect cancer cells using voltage noise caused by cell adhesion which is recorded by high-density CMOS-based microelectrode arrays. We analyze our data in terms of spectral power density for two different types of arrays, each of them being optimized in a different working regime.
en
Research Areas:
Visual Computing and Human-Centered Technology: 20% Biological and Bioactive Materials: 30% Sensor Systems: 50%
