COMET Zentrum Chemical Systems Engineering CHASE: FFG Projektnummer 868.615 (FFG - Österr. Forschungsförderungs- gesellschaft mbH) Tumor und Lymphknoten auf einer Chip Plattform für Krebsstudien: 953234 (European Commission)
-
Additional information:
Extracellular vesicles (EVs) are nanosized particles excreted by cells, which are associated with various physiological and pathological functions. They play a key role in intercell communication and are used as transport vehicles for various cell components [1]. State of the art analysis methods are not able to provide label free chemical information at the single vesicle level [2], hence, new analysis techniques are required to study the chemical difference within EV (sub-)population. We introduce a protocol to profile structure and composition of individual EVs with the help of photothermal scanning probe infrared spectroscopy (AFM-IR).
-
Research Areas:
Materials Characterization: 50% Biological and Bioactive Materials: 50%