<div class="csl-bib-body">
<div class="csl-entry">Mühlberger, M. M., Kopp, S., Deyett, A. A., Pribyl, M., Haslinger, M. J., Siegel, A. M., Taus, P., Guillén, E., Torres-Caballero, A., Baltov, B., Netzer, M. A., Prado Lopez, S., Yde, L., Stensborg, J., Mendjan, S., Hering, S., & Wanzenböck, H. (2023). Nanoimprinted hierarchical micro-/nanostructured substrates for the growth of cardiomyocyte fibers. <i>Nanomanufacturing</i>, <i>3</i>(4), 416–433. https://doi.org/10.3390/nanomanufacturing3040026</div>
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dc.identifier.uri
http://hdl.handle.net/20.500.12708/191002
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dc.description.abstract
Investigating the behavior of cardiomyocytes is an important part of drug development. We present a structure and a related nanoimprint-based fabrication method, where the cardiomyocytes form isolated fibers, which is beneficial for drug testing, more closely representing the structure of the cardiomyocytes in vivo. We found that channel structures with walls with a rough top surface stimulate cardiomyocytes to form such fibers, as desired. Nanoimprint lithography is used as a fast and cost-efficient method to fabricate our hierarchically structured cell growth substrates.
en
dc.language.iso
en
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dc.publisher
MDPI
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dc.relation.ispartof
Nanomanufacturing
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dc.rights.uri
http://creativecommons.org/licenses/by/4.0/
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dc.subject
nanoimprint lithography
en
dc.subject
cell growth
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dc.subject
cardiomyocytes
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dc.subject
fiber formation
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dc.title
Nanoimprinted hierarchical micro-/nanostructured substrates for the growth of cardiomyocyte fibers
