Ell, M. F., Bui, M. T., Prado Lopez, S., & Zeck, G. (2023). Electrical Recording of Effects of Chemotherapeutic Treatment on Cancer Spheroids. In 2023 IEEE SENSORS (pp. 1–4). IEEE. https://doi.org/10.34726/5342
E363-50 - Services des Instituts E363 - Institut für Biomedizinische Elektronik
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Published in:
2023 IEEE SENSORS
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ISBN:
979-8-3503-0387-2
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Date (published):
2023
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Event name:
2023 IEEE SENSORS
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Event date:
29-Oct-2023 - 1-Nov-2023
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Event place:
Vienna, Austria
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Number of Pages:
4
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Publisher:
IEEE, Piscataway
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Keywords:
Microelectrodes; Spectroscopy; Power system measurements; Adhesives; Optical recording; Optical sensors; Optical noise; CMOS-based microelectrode arrays; Cell adhesion noise spectroscopy; Colorectal cancer cells; Spheroids; Anti-cancer therapeutics
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Abstract:
Monitoring cells on substrates time-continuously without relying on optical microscopy imaging is of broad interest in biotechnological applications. We propose an approach to electrically investigate cytotoxic effects of a chemotherapeutic treatment on cancer cells using cell adhesion noise spectroscopy. Recordings are taken with high-density microelectrode arrays, data are analyzed in terms of spectral power density.
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Research Areas:
Visual Computing and Human-Centered Technology: 20% Biological and Bioactive Materials: 30% Sensor Systems: 50%
