In recent years, mechanochemistry has emerged as a revolutionary tool in modern synthetic chemistry. Especially en route to more sustainable and environmentally benign chemical processes, mechanochemical transformations are privileged, since this approach offers a unique advantage: the ability to conduct conventional synthetic reactions without the need for solvents coupled with rapid reaction kinetics. These unique features make mechanochemistry highly attractive for both industrial applications and fundamental research across diverse fields, including material science, inorganic chemistry, and organic chemistry.
Hence, we started a program to investigate the possibilities for carrying out fundamental organic transformations under solvent free conditions using a mechanochemical setup. Herein we report our results on mechanochemical Tsuji-Trost allylations, Wittig reactions, and Diels-Alder reactions as well as multistep sequences thereof.
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Research facilities:
Zentrum für Kernspinresonanzspektroskopie
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Project title:
Substitution von gasförmigen Reagenzien durch Feststoffe: P 33064-N (FWF - Österr. Wissenschaftsfonds) C-H Activation Towards Industrial Renewal: 860762 (European Commission)
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Research Areas:
Sustainable Production and Technologies: 25% Efficient Utilisation of Material Resources: 25% Beyond TUW-research focus: 50%