Bachmann, S., Iori, G., Raum, K., Pahr, D. H., & Synek, A. (2025). Predicting physiological hip joint loads with inverse bone remodeling using clinically available QCT images. Computer Methods and Programs in Biomedicine, 267, Article 108805. https://doi.org/10.1016/j.cmpb.2025.108805
Humans; Finite Element Analysis; Weight-Bearing; Male; Female; Biomechanical Phenomena; Bone adaptation, load estimation; Clinical feasibility; Homogenized finite-element; Inverse remodeling; Physiological loading; loading history; Tomography, X-Ray Computed; Hip Joint; Bone Remodeling
en
Abstract:
Assessing joint-level loading conditions in vivo is challenging due to invasive measurement or complex computation. Inverse bone remodeling (IBR) offers a different approach by recovering the loading conditions directly from computed tomography (CT) images of the bone microstructure by finding the magnitudes to a set of load cases that load the bone optimally, i.e., maximally homogeneously. An efficient IBR method was recently proposed based on homogenized finite element (hFE) models. This study compared the hip joint load predictions of hFE-based IBR with clinically feasible CT scans to those obtained with the current gold standard, micro-FE-based IBR.
en
Research Areas:
Biological and Bioactive Materials: 30% Modeling and Simulation: 40% Structure-Property Relationsship: 30%
CC BY 4.0
