We present design, synthesis and application of basic chiral ionic liquids based on commercially available
(S)-proline. This new set of chiral ionic liquids was specifically designed to replace trifluoroacetic
acid in enamine-based organocatalysis for asymmetric C C bond formation. Based on their permanent
charge, these chiral ionic liquids could be applied as organocatalysts in asymmetric aldol reaction of 4-
nitrobenzaldehyde and acetone, and good yields and selectivities up to 80%ee could be obtained without
additional acid.
en
Research Areas:
außerhalb der gesamtuniversitären Forschungsschwerpunkte: 50% Sustainable Production and Technologies: 50%
-
Science Branch:
Chemie Technische Chemie, Brennstoff- und Mineralöltechnologie
