Record link: 
http://hdl.handle.net/20.500.12708/186960
-
Title: 
Supported Ionic Liquid Phase (SILP) Allylic Alkylation of Amines in Continuous Flow
en
Citation: 
Stagel, K., Pálvölgyi, Á. M., Delmas, C., Schnürch, M., & Schröder, K. (2023). Supported Ionic Liquid Phase (SILP) Allylic Alkylation of Amines in Continuous Flow. ChemCatChem, Article e202300381. https://doi.org/10.1002/cctc.202300381
-
Publisher DOI: 
10.1002/cctc.202300381
-
Publication Type: 
Article - Original Research Article
en
Language: 
English
-
Authors: 
Stagel, Kristof 
Pálvölgyi, Ádám Márk 
Delmas, Clémence 
Schnürch, Michael 
Schröder, Katharina 
-
Organisational Unit: 
E163-03-5 - Forschungsgruppe Nachhaltige organische Synthese und Katalyse 
E163-03-4 - Forschungsgruppe Bioorganische Synthesechemie 
-
Journal: 
ChemCatChem 
-
ISSN: 
1867-3880
-
Date (published): 
6-Apr-2023
-
Number of Pages: 
6
-
Publisher: 
WILEY-V C H VERLAG GMBH
-
Peer reviewed: 
Yes
-
Keywords: 
chiral catalyst; continuous flow; ionic liquid; SILP; Tsuji-Trost reaction
en
Abstract: 
We present the use of Pd-complex-containing supported ionic liquid phases (SILPs) as a novel approach for continuous-flow allylic alkylation of N-nucleophiles. This immobilization strategy gave simple access to air-tolerating catalyst frameworks, providing rapid and convenient access to various achiral and chiral N-allylation products. Under optimized conditions, the flow-reaction could be maintained for 3.5 hours with constant product output; meanwhile, only a marginal 0.7 wt % of ionic liquid leaching and no detectable palladium-complex leaching could be observed.
en
Research Areas: 
Sustainable Production and Technologies: 100%
-
Science Branch: 
1040 - Chemie: 60%
2040 - Chemische Verfahrenstechnik: 20%
3012 - Pharmazie, Pharmakologie, Toxikologie: 20%
-
Appears in Collections:
Article

Show full item record

Page view(s)

59
checked on Dec 1, 2023

Google ScholarTM

Check