Ultra-short pulse laser processing has emerged as a powerful technology for high precision material processing offering minimal thermal impact. The rapid evolution of this field is driven by its applications in advanced manufacturing, microelectronics, and medical device fabrication, where precision and efficiency are paramount. However, the underlying physical phenomena, including laser-material interactions, are profoundly complex. The interplay of ultrafast laser pulses with varying material properties and the intricate dynamics of absorption and ablation mechanisms presents significant challenges in fully understanding the processes at play. To address these challenges, our team has developed a cutting-edge 3D multiphysical simulation tool, based on our in-house "Compressible Mass-of-Fluid" model. This tool has been enhanced with material-dependent absorption models and a two-temperature model, enabling a more accurate representation of the rapid energy transfer and thermal responses during laser processing. The simulation framework is designed to explore the intricate dependencies of laser parameters and material characteristics, providing crucial insights into the mechanisms that govern ablation processes. In this talk, we will delve into selected topics that highlight the capabilities of our simulation tool in unraveling the complexities of ultra-short pulse laser processing. By investigating the influence of various laser parameters and material properties, we aim to enhance the understanding of ablation mechanisms, ultimately paving the way for optimized processing strategies in future applications. This comprehensive approach not only advances the theoretical understanding but also holds practical implications for improving precision and efficiency in laser-based manufacturing.