Syntheses and biological applications of selected n-containing heterocycles: Recent advances of derivatives of Aziridines, Triazoles, and Piperazines

Abstract

Heterocycles are organic cyclic compounds characterized by one or more heteroatoms in their structures. The most diffuse examples in chemistry are the five- or six-membered heterocycles bearing a nitrogen, oxygen, and/or sulfur atoms. They are the largest and most varied family of organic compounds showing several biological activities and represent more than 50% of the nowadays existing drugs. In this chapter, the syntheses and biological applications of aziridine, triazole, and piperazine derivatives are reported, considering their importance in organic chemistry and medicinal chemistry.