Title: Synthesis of 20ßOH-NorMD, a long-term urinary metandienone metabolite
Language: English
Authors: Kratena, Nicolas 
Qualification level: Diploma
Keywords: Doping; Analyse; Synthese; Steroid
Doping; Analysis; Synthesis; Steroid
Advisor: Gärtner, Peter  
Assisting Advisor: Enev, Valentin 
Issue Date: 2015
Number of Pages: 45
Qualification level: Diploma
The goal of this thesis was a good-yielding chemical synthesis of a metandienone metabolite which is of interest in doping analysis. Compound 20ßOH-NorMD (IUPAC: 17ß-hydroxymethyl-17--methyl-18-norandrosta-1,4,13-triene-3-one) has been identified as a long-term urinary metabolite which can be detected and attributed to metandienone up to almost 3 weeks after exposure. The chemical synthesis of another isomer: 20-OH-NorMD has been described before by Parr et al.; Zöllner et al. reported a chemoenzymatic way to 20ßOH-NorMD but no chemical synthesis was yet published.
URI: https://resolver.obvsg.at/urn:nbn:at:at-ubtuw:1-86281
Library ID: AC12611472
Organisation: E163 - Institut für Angewandte Synthesechemie 
Publication Type: Thesis
Appears in Collections:Thesis

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