Title: | Synthesis of 20ßOH-NorMD, a long-term urinary metandienone metabolite | Language: | English | Authors: | Kratena, Nicolas | Qualification level: | Diploma | Keywords: | Doping; Analyse; Synthese; Steroid Doping; Analysis; Synthesis; Steroid |
Advisor: | Gärtner, Peter ![]() |
Assisting Advisor: | Enev, Valentin | Issue Date: | 2015 | Number of Pages: | 45 | Qualification level: | Diploma | Abstract: | The goal of this thesis was a good-yielding chemical synthesis of a metandienone metabolite which is of interest in doping analysis. Compound 20ßOH-NorMD (IUPAC: 17ß-hydroxymethyl-17--methyl-18-norandrosta-1,4,13-triene-3-one) has been identified as a long-term urinary metabolite which can be detected and attributed to metandienone up to almost 3 weeks after exposure. The chemical synthesis of another isomer: 20-OH-NorMD has been described before by Parr et al.; Zöllner et al. reported a chemoenzymatic way to 20ßOH-NorMD but no chemical synthesis was yet published. |
URI: | https://resolver.obvsg.at/urn:nbn:at:at-ubtuw:1-86281 http://hdl.handle.net/20.500.12708/4875 |
Library ID: | AC12611472 | Organisation: | E163 - Institut für Angewandte Synthesechemie | Publication Type: | Thesis Hochschulschrift |
Appears in Collections: | Thesis |
Files in this item:
File | Description | Size | Format | |
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Synthesis of ssOH-NorMD a long-term urinary metandienone metabolite.pdf | 5.08 MB | Adobe PDF | ![]() View/Open |
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