Title: New synthesis pathways for a ß-lactamase inhibitor
Language: English
Authors: Himmelbauer, Daniel 
Qualification level: Diploma
Keywords: Antibiotics; beta-Lactamase Inhibitor; Avibactam; Synthesis
Advisor: Gärtner, Peter  
Issue Date: 2016
Number of Pages: 72
Qualification level: Diploma
Bacterial strains came under enormous pressure due the overuse of ß-lactam antibiotics. In a selective process only the resistant strains survived and new ß-lactamase resistances were formed. Avibactam is the first non-ß-lactam ß-lactamase inhibitor which is used clinically since more than 20 years. Compared to its predecessors it has unique properties and a wider scope of activity against ß-lactamases. By developing a new synthetic route for avibactam, the originator process patent can be circumvented and it is possible to be the first generic company on the market.
URI: https://resolver.obvsg.at/urn:nbn:at:at-ubtuw:1-127572
Library ID: AC13319399
Organisation: E163 - Institut für Angewandte Synthesechemie 
Publication Type: Thesis
Appears in Collections:Thesis

Files in this item:

File Description SizeFormat
New synthesis pathways for a ss-lactamase inhibitor.pdf4.93 MBAdobe PDFThumbnail
Show full item record

Page view(s)

checked on Feb 21, 2021


checked on Feb 21, 2021

Google ScholarTM


Items in reposiTUm are protected by copyright, with all rights reserved, unless otherwise indicated.