Title: Microdevices for realisation of coaxial sheath flows : simulation, fabrication and characterisation
Language: English
Authors: Pärr, Günter 
Qualification level: Diploma
Advisor: Vellekoop, Michael
Issue Date: 2007
Number of Pages: 59
Qualification level: Diploma
Die Arbeit beschreibt die Entwicklung, Herstellung und die experimentelle Überprüfung von so genannten Microfluidic-Devices welche im Stande sind Probeflüssigkeiten und Partikel (wie zum Beispiel Moleküle und Zellen) innerhalb eines Mikrokanals zu positionieren und auszurichten. Das dazu verwendete physikalische Konzept wird als "Sheath-Flow" Technik bezeichent. Es konnten sowohl koaxiale als auch nicht koaxiale Strömungen der Probeflüssigkeiten realisiert werden. Als Messprinzip wurde konfokale Laser-Mikroskopie verwendet.

This master thesis describes the development and design of microfluidic devices which use sheath flows to align and focus sample flows within a micro channel. The measurement of diluted particles (e.g.
cells, molecules) in a MEMS device for analytical purposes for example in life science and biotechnology makes it necessary to deal with detailed problems in microfluidics. Especially when it comes to single particle detection or manipulation it is important to ensure that the particles are passing the transducer area only one by one. This requires sharp focusing techniques. One elegant solution is to use hydrodynamic focusing in combination with sheath flows. The contribution in this thesis deals with the design and simple realization of microfluidic devices for focusing and 3D-alignment of coaxial and non-coaxial micro scale sample flows. For the experimental verification confocal laser microscope measurements were used.
Keywords: MEMS; Mikrochip; koaxial; Schichtfluss; Fluoreszenz; Mikrosystemtechnik; Fluidik; Mikrofluidik; Strömungstechnik
MEMS; microdevice; Lab; coaxial; sheathflows; microchannel; microchip; confocal; fluidic; microfluidic
URI: https://resolver.obvsg.at/urn:nbn:at:at-ubtuw:1-19565
Library ID: AC05034575
Organisation: E366 - Institut für Sensor- und Aktuatorsysteme 
Publication Type: Thesis
Appears in Collections:Thesis

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