Record link: 
http://hdl.handle.net/20.500.12708/221990
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Title: 
CGT 4.0: a distant dream or inevitable future? Smart process automation is critical to make efficient scalability of CGT manufacturing a reality
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Citation: 
Szarzynski, A., Spadiut, O., Reisbeck, M., Jobst, G., Paterson, R., Kamenskaya, A., Gateau, E., Lesch, H. P., Henry, L., & Kozma, B. (2025). CGT 4.0: a distant dream or inevitable future? Smart process automation is critical to make efficient scalability of CGT manufacturing a reality. Frontiers in Bioengineering and Biotechnology, 13, Article 1563878. https://doi.org/10.3389/fbioe.2025.1563878
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Publisher DOI: 
10.3389/fbioe.2025.1563878
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Publication Type: 
Article - Other Contribution
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Language: 
English
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Authors: 
Szarzynski, Aleksander 
Spadiut, Oliver 
Reisbeck, Mathias 
Jobst, Gerhard 
Paterson, Rachel 
Kamenskaya, Anna 
Gateau, Emilie 
Lesch, Hanna P. 
Henry, Luc 
Kozma, Bence 
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Organisational Unit: 
E166-04-2 - Forschungsgruppe Integrierte Bioprozessentwicklung 
E166-04-1 - Forschungsgruppe Bioprozess-Technologie 
E056-12 - Fachbereich ENROL DP 
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Journal: 
Frontiers in Bioengineering and Biotechnology 
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ISSN: 
2296-4185
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Date (published): 
19-Mar-2025
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Number of Pages: 
6
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Publisher: 
FRONTIERS MEDIA SA
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Peer reviewed: 
No
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Keywords: 
PAT; automation; cell and gene therapy; digital twin; manufacturing; sensors; single-use; viral vector
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Research facilities: 
Analytical Instrumentation Center 
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Project title: 
PAT4CGT: 101070922 (European Commission) 
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Research Areas: 
Efficient Utilisation of Material Resources: 10%
Modeling and Simulation: 10%
Beyond TUW-research focus: 80%
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Science Branch: 
3040 - Medizinische Biotechnologie: 50%
2090 - Industrielle Biotechnologie: 25%
3020 - Klinische Medizin: 25%
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